Department of Otorhinolaryngology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea.
Am J Rhinol Allergy. 2011 May-Jun;25(3):117-21. doi: 10.2500/ajra.2011.25.3630.
Chronic rhinosinusitis (CRS) is one of the most common inflammatory diseases with multiple etiologies. Despite its high prevalence, risk factors influencing its prevalence have not been thoroughly revealed. Therefore, we investigated the prevalence and risk factors of CRS in Korea.
The 4098 subjects that participated in the Korea National Health and Nutrition Examination Survey were included in the study. Risk factors were categorized into sociodemographic and personal medical factors. Univariate and multivariate analyses were performed to identify significant risk factors of CRS. In addition, population attributable risks of the significant factors were calculated to estimate the effect on the population level.
The prevalence of CRS in Korea was 6.95%. Among sociodemographic factors, male sex, old age, and heavy stress were significantly related with CRS. Influenza vaccination, septal deviation, and persistent allergic rhinitis were significant personal medical risk factors of CRS. Among these risk factors, persistent/moderate to severe allergic rhinitis was proven to be the most significant risk factor for CRS at the population level.
Although the prevalence and risk factors vary according to time, place, and diagnostic criteria, periodic epidemiological study on CRS is necessary to reduce socioeconomic expenditure and establish an improved national health care policy.
慢性鼻-鼻窦炎（CRS）是一种具有多种病因的最常见炎症性疾病之一。尽管其患病率较高，但影响其患病率的危险因素尚未得到充分揭示。因此，我们调查了韩国 CRS 的患病率和危险因素。
本研究纳入了参加韩国国家健康和营养检查调查的 4098 名受试者。危险因素分为社会人口统计学和个人医疗因素。进行单因素和多因素分析以确定 CRS 的显著危险因素。此外，还计算了显著因素的人群归因风险，以估计其对人群水平的影响。
韩国 CRS 的患病率为 6.95%。在社会人口统计学因素中，男性、年龄较大和压力较大与 CRS 显著相关。流感疫苗接种、鼻中隔偏曲和持续性过敏性鼻炎是 CRS 的显著个人医疗危险因素。在这些危险因素中，持续性/中重度过敏性鼻炎被证明是人群水平上 CRS 的最显著危险因素。
尽管患病率和危险因素因时间、地点和诊断标准而异，但仍有必要定期进行 CRS 的流行病学研究，以减少社会经济支出并制定改善的国家医疗保健政策。
