School of Electrical and Computer Engineering, Shiraz University, Shiraz, Iran.
Comput Biol Med. 2011 Aug;41(8):619-32. doi: 10.1016/j.compbiomed.2011.05.013. Epub 2011 Jun 16.
In this paper a novel automatic approach to identify brain structures in magnetic resonance imaging (MRI) is presented for volumetric measurements. The method is based on the idea of active contour models and support vector machine (SVM) classifiers. The main contributions of the presented method are effective modifications on brain images for active contour model and extracting simple and beneficial features for the SVM classifier. The segmentation process starts with a new generation of active contour models, i.e., vector field convolution (VFC) on modified brain images. VFC results are brain images with the least non-brain regions which are passed on to the SVM classification. The SVM features are selected according to the structure of brain tissues, gray matter (GM), white matter (WM), and cerebrospinal fluid (CSF). SVM classifiers are trained for each brain tissue based on the set of extracted features. Although selected features are very simple, they are both sufficient and tissue separately effective. Our method validation is done using the gold standard brain MRI data set. Comparison of the results with the existing algorithms is a good indication of our approach's success.
本文提出了一种新的自动方法,用于对磁共振成像 (MRI) 中的脑结构进行体积测量。该方法基于主动轮廓模型和支持向量机 (SVM) 分类器的思想。所提出方法的主要贡献在于对主动轮廓模型进行了有效的脑图像修改,并为 SVM 分类器提取了简单而有益的特征。分割过程从修改后的脑图像上的新一代主动轮廓模型(即矢量场卷积 (VFC))开始。VFC 的结果是具有最少非脑区域的脑图像,这些图像被传递给 SVM 分类。根据脑组织、灰质 (GM)、白质 (WM) 和脑脊液 (CSF) 的结构选择 SVM 特征。基于提取的特征集为每种脑组织训练 SVM 分类器。虽然选择的特征非常简单,但它们既足够又分别对组织有效。我们的方法验证是使用黄金标准脑 MRI 数据集完成的。将结果与现有算法进行比较,很好地表明了我们方法的成功。