Golovkina T V, Tikhonenko A T, Vassetzky N S, Sheftel B I, Gudkov A V
Laboratory of Molecular Genetics, National Cancer Research Center, USSR Academy of Medical Sciences, Moscow.
Virus Genes. 1990 Jun;4(1):85-92. doi: 10.1007/BF00308568.
Sequences (MRS) distantly related to mouse mammary tumor virus (MMTV) were found in genomes of a wide range of mammalian species using blot hybridization. The number of MRS copies and the degree of their homology with the hybridization probe varied and did not correlate with the taxonomic position of the species. Nevertheless, within a genus the set of MRS was species specific and reflected the taxonomic relation between the species. MRS were also found in avian genomes and the degree of their homology did not correlate with the taxonomic position of the species either. The origin and distribution of MRS is discussed on the basis of the authors' and published data.
利用印迹杂交技术在多种哺乳动物的基因组中发现了与小鼠乳腺肿瘤病毒（MMTV）远缘相关的序列（MRS）。MRS的拷贝数及其与杂交探针的同源程度各不相同，且与物种的分类地位无关。然而，在一个属内，MRS的集合具有物种特异性，并反映了物种之间的分类关系。在鸟类基因组中也发现了MRS，其同源程度同样与物种的分类地位无关。基于作者本人的数据和已发表的数据，对MRS的起源和分布进行了讨论。
