Instituto de Medicina Forense, Universidad Veracruzana, Juan Pablo II, Esq. Reyes Heroles Fracc. Costa Verde, Boca del Rio, C.P: 94294, Veracruz, Ver., Mexico.
Universidad de Occidente, Los Mochis, Sin., Mexico.
Environ Monit Assess. 2018 Mar 10;190(4):206. doi: 10.1007/s10661-018-6581-y.
The population that lives in areas where organochlorine pesticides were spread in the past is still exposed to them through contaminated food, particulate matter, and vapors. Due to their lipophilic properties and resistance to metabolic reactions, they accumulate in tissues and fluids rich in lipids. The aim of the study was to monitor the concentrations of organochlorine pesticides in forensic adipose tissue samples of adult inhabitants of Veracruz City, Mexico, and compare their time trend levels from 1988 to 2014. During the study, hexachlorobenzene (HCB); lindane; β-hexachorocyclohexane; p,p'-dichlorodiphenyldichloroethylene (pp'DDE); p,p'-dichlorodiphenyldichloroethane (p,p'-DDT); and o,p'-dichlorodiphenyldichloroethane (o,p'-DDT) were determined. Our survey was divided into two periods: first, from the years 1988 to 1999, during which DDT was allowed to fight malaria and dengue vectors and the second from the years 2001 to 2014, after the DDT ban. A total of 1435 samples were analyzed. There were substantial differences in the forecasted time trend values of p,p'-DDE and p,p'-DDT in human adipose tissue samples in the two different periods. During the first period, p,p'-DDE decrease time trend was 1.198 mg/kg on lipid base per year; for the second one, decrease was 0.128 mg/kg on lipid base per year. p,p'-DDT decreased 0.507 mg/kg on lipid base during the first period and 0.039 mg/kg on lipid base for the second. The different concentrations may be explained by the cessation of fresh exposure after the first period and a more equilibrated decontamination tendency during the second period. This model was useful to show the decrease in the concentration of pesticides in human adipose tissue samples.
过去在有机氯农药喷洒过的地区生活的人群仍然通过受污染的食物、颗粒物和蒸气接触到这些农药。由于其亲脂性和对代谢反应的抗性，它们会在富含脂肪的组织和液体中积累。本研究的目的是监测墨西哥韦拉克鲁斯市成年居民法医脂肪组织样本中有机氯农药的浓度，并比较 1988 年至 2014 年的时间趋势水平。在研究过程中，测定了六氯苯（HCB）；林丹；β-六氯环己烷；p,p'-二氯二苯二氯乙烯（pp'DDE）；p,p'-二氯二苯二氯乙烷（p,p'-DDT）和 o,p'-二氯二苯二氯乙烷（o,p'-DDT）。我们的调查分为两个时期：第一时期为 1988 年至 1999 年，在此期间允许使用滴滴涕来防治疟疾和登革热媒介；第二时期为 2001 年至 2014 年，滴滴涕被禁用。共分析了 1435 个样本。在两个不同时期，人体脂肪组织样本中 p,p'-DDE 和 p,p'-DDT 的预测时间趋势值存在显著差异。在第一时期，p,p'-DDE 下降的时间趋势为每年 1.198 毫克/千克脂质基础；在第二时期，每年下降 0.128 毫克/千克脂质基础。在第一时期，p,p'-DDT 以脂质基础下降 0.507 毫克/千克，在第二时期以脂质基础下降 0.039 毫克/千克。不同的浓度可能是由于第一时期后新鲜暴露的停止和第二时期更均衡的脱污染趋势造成的。该模型有助于展示人体脂肪组织样本中农药浓度的下降。
