Hypertrophic Cardiomyopathy Center, Division of Cardiology, Tufts Medical Center, Boston, Massachusetts, USA.
Am J Cardiol. 2011 Aug 15;108(4):612-3. doi: 10.1016/j.amjcard.2011.03.094. Epub 2011 Jun 20.
The investigators report similar phenotypes of hypertrophic cardiomyopathy with left ventricular apical aneurysm and thrombus in 2 brothers aged 8 years apart. This report highlights the genetic predisposition for this unique, high-risk phenotype, the issue of prophylactic anticoagulation, and the importance of nonstandard echocardiographic imaging views in the assessment of these patients.
研究者报告了 2 例年龄相差 8 岁的肥厚型心肌病伴左室心尖部瘤和血栓形成的兄弟具有相似的表型。本报告强调了这种独特的、高风险表型的遗传易感性、预防性抗凝的问题，以及在评估这些患者时非标准超声心动图成像切面的重要性。
