Sawant Apurva, Mankeshwar Ranjit, Shah Swarup, Raghavan Rani, Dhongde Gargi, Raje Himanshu, D'souza Shoba, Subramanium Aarti, Dhairyawan Pradnya, Todur Seema, Ashavaid Tester F
Research Laboratories, P. D. Hinduja National Hospital & Medical Research Centre, Mumbai 400016, India.
Cholesterol. 2011;2011:920983. doi: 10.1155/2011/920983. Epub 2011 May 19.
Background. Metabolic syndrome (MS) is characterised by a constellation of individual risk factors of cardiovascular disease. Materials and Methods. The current study was a population-based survey of cohort of subjects in the metropolitan city of Mumbai. A total of 548 subjects, who attended the CARDIAC evaluation camp, were recruited in the study. Participants with complete fasting lipid profiles, blood glucose, and known cardiac risk markers were evaluated. Results. On applying modified NCEP ATP III, we found out that nearly 95% of the subjects had at least one abnormal parameter. We found the prevalence of MS in our study population to be 19.52%. The prevalence of MS in males was almost double than females (P = .008). The overall prevalence of BMI (>23 kg/m(2)) was 79.01%. Increased hypertriglyceridemia and decreased levels of HDL-C were found to be more in males (P < .0001). Conclusion. The low percentage of subjects with normal and controlled parameters suggests that there is a need for awareness programs and lifestyle interventions for the prevention and control of MS.
背景。代谢综合征（MS）的特征是一系列心血管疾病的个体危险因素。材料与方法。本研究是对孟买大都市地区人群队列进行的一项基于人群的调查。共有548名参加心脏评估营的受试者被纳入研究。对具有完整空腹血脂谱、血糖和已知心脏风险标志物的参与者进行了评估。结果。应用改良的NCEP ATP III标准，我们发现近95%的受试者至少有一项异常参数。我们发现研究人群中MS的患病率为19.52%。男性MS的患病率几乎是女性的两倍（P = 0.008）。BMI（>23 kg/m²）的总体患病率为79.01%。男性中高甘油三酯血症增加和高密度脂蛋白胆固醇水平降低更为明显（P < 0.0001）。结论。正常和可控参数的受试者比例较低，这表明需要开展提高认识的项目和进行生活方式干预，以预防和控制MS。
