Dakshinamurthy Senkadhirdasan, Saxena Vartika, Kumari Ranjeeta, Mirza Anissa Atif, Dhar Minakshi
Department of Community and Family Medicine, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Department of Biochemistry, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Indian J Community Med. 2020 Oct-Dec;45(4):516-521. doi: 10.4103/ijcm.IJCM_24_20. Epub 2020 Oct 28.
Noncommunicable diseases include heart disease, stroke, cancer, diabetes, and chronic lung diseases and are collectively responsible for almost 70% of all deaths worldwide. Metabolic syndrome (MetS) predisposes to coronary artery disease irrespective of age, gender, or family history of diabetes.
The aims of this study were as follows: (1) to assess the prevalence and its predictors of obesity among the urban population, (2) to analyze the association of obesity with MetS, and (3) to analyze the correlation of obesity with different components of MetS.
A community-based cross-sectional study was conducted in an urban area of Rishikesh. The World Health Organization STEPS instrument and protocol were used for the assessment of risk factors and measurements. The sample size was calculated to be 478. Data were analyzed using SPSS version 20.0. Appropriate statistical tests for bivariate and multivariate analysis were done. < 0.05 was considered statistically significant.
The prevalence of MetS among obese individuals was significantly higher (57%) according to the National Cholesterol Educational Program Adult Treatment Panel 3 definition ( < 0.001). The prevalence of MetS in male and female obesity was 56.8% and 57.1%, respectively. Body mass index was significantly correlated with systolic blood pressure (BP) ( = 0.238, = 0.001), diastolic BP ( = 0.281, = 0.001), Fasting blood glucose (FBG) ( = 0.136, = 0.003), and triglycerideTriglycerides (TG) ( = 0.12, = 0.009) and negatively correlated with High Density Lipoproteins (HDL) ( = -0.041, = 0.37). Whereas, waist-hip ratio was significantly correlated with systolic BP ( = 0.277, = 0.001), diastolic BP ( = 0.251, = 0.001), FBG ( = 0.232, = 0.001), and TG ( = 0.273, = 0.001) and not with HDL ( = 0.033, = 0.466).
As the prevalence of MetS is higher among obese individuals, health interventions required to reduce the morbidity/mortality and need to be addressed in adult populations.
非传染性疾病包括心脏病、中风、癌症、糖尿病和慢性肺病，这些疾病加起来导致了全球近70%的死亡。无论年龄、性别或糖尿病家族史如何，代谢综合征（MetS）都易引发冠状动脉疾病。
本研究的目的如下：（1）评估城市人口中肥胖的患病率及其预测因素；（2）分析肥胖与代谢综合征之间的关联；（3）分析肥胖与代谢综合征不同组分之间的相关性。
在瑞诗凯诗的一个市区开展了一项基于社区的横断面研究。采用世界卫生组织的STEPS工具和方案来评估危险因素并进行测量。计算得出样本量为478。使用SPSS 20.0版对数据进行分析。对双变量和多变量分析进行了适当的统计检验。P<0.05被认为具有统计学意义。
根据美国国家胆固醇教育计划成人治疗小组第三次报告的定义，肥胖个体中代谢综合征的患病率显著更高（57%）（P<0.001）。男性和女性肥胖者中代谢综合征的患病率分别为56.8%和57.1%。体重指数与收缩压（r = 0.238，P = 0.001）、舒张压（r = 0.281，P = 0.001）、空腹血糖（FBG）（r = 0.136，P = 0.003）和甘油三酯（TG）（r = 0.12，P = 0.009）显著相关，与高密度脂蛋白（HDL）呈负相关（r = -0.041，P = 0.37）。而腰臀比与收缩压（r = 0.277，P = 0.001）、舒张压（r = 0.251，P = 0.001）、空腹血糖（r = 0.232，P = 0.001）和甘油三酯（r = 0.273，P = 0.001）显著相关，与高密度脂蛋白无关（r = 0.033，P = 0.466）。
由于肥胖个体中代谢综合征的患病率较高，需要采取健康干预措施来降低发病率/死亡率，并且需要在成年人群中加以解决。
