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本文引用的文献

1
Label-free electrical detection of pyrophosphate generated from DNA polymerase reactions on field-effect devices.场效应器件上 DNA 聚合酶反应生成的焦磷酸根的无标记电检测。
Analyst. 2012 Mar 21;137(6):1351-62. doi: 10.1039/c2an15930a. Epub 2012 Jan 19.
2
Molecular sensing using monolayer floating gate, fully depleted SOI MOSFET acting as an exponential transducer.使用作为指数转换器的单层浮动栅极、全耗尽 SOI MOSFET 进行分子感应。
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Direct detection of molecular biorecognition by dipole sensing mechanism.通过偶极传感机制直接检测分子生物识别
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Chemosensors for pyrophosphate.用于焦磷酸的化学传感器。
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Chemical sensors with integrated electronics.集成电子的化学传感器。
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Field effect of screened charges: electrical detection of peptides and proteins by a thin-film resistor.屏蔽电荷的场效应：通过薄膜电阻对肽和蛋白质进行电学检测。
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Naked-eye detection of phosphate ions in water at physiological pH: a remarkably selective and easy-to-assemble colorimetric phosphate-sensing probe.生理pH条件下水中磷酸根离子的裸眼检测：一种具有显著选择性且易于组装的比色法磷酸根传感探针。
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A sequencing method based on real-time pyrophosphate.一种基于实时焦磷酸的测序方法。
Science. 1998 Jul 17;281(5375):363, 365. doi: 10.1126/science.281.5375.363.

用于焦磷酸盐无标记电检测的表面固定螯合剂。

Surface immobilizable chelator for label-free electrical detection of pyrophosphate.

机构信息

Integrated Biosystems Lab, Intel Labs, Intel Corporation, 2200 Mission College Blvd., Santa Clara, CA 95054, USA.

出版信息

Chem Commun (Camb). 2011 Aug 7;47(29):8310-2. doi: 10.1039/c1cc12073e. Epub 2011 Jun 20.

DOI:10.1039/c1cc12073e
PMID:21687892
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3361515/
Abstract

A new pyrophosphate (PPi) chelator was designed for surface-sensitive electrical detection of biomolecular reactions. This article describes the synthesis of the PPi-selective receptor, its surface immobilization and application to label-free electrical detection on a silicon-based field-effect transistor (FET) sensor.

摘要

一种新的焦磷酸（PPi）螯合剂被设计用于生物分子反应的表面敏感电检测。本文描述了 PPi 选择性受体的合成、表面固定化及其在基于硅的场效应晶体管（FET）传感器上的无标记电检测中的应用。