Martin W B, Castrucci G, Frigeri F, Ferrari M
"Vittorio Cilli" University Laboratory of Virology, School of Veterinary Medicine, University of Perugia, Italy.
Comp Immunol Microbiol Infect Dis. 1990;13(2):75-84. doi: 10.1016/0147-9571(90)90519-y.
Bovine herpesvirus 1 (BHV-1) isolates (Cooper-type strain 4975 and Oxford) were compared in neutralization tests with the bovine herpesvirus 4 (BHV-4) isolate (85/16 TV) and the herpesviruses of red deer (D2839/1) and goats (E/CH). Hyperimmune antiserum was prepared in rabbits against the plaque-selected viruses and endpoint and kinetic neutralization test were made. BHV-4 was clearly different from the other four viruses. The closely-related BHV-1 strains were also related in these tests to the red deer herpesvirus. The Oxford strain seemed rather closer antigenically than the Cooper-type strain to the red deer herpesvirus. Antiserum to the caprine herpesvirus failed to neutralize either BHV-1 strain or red deer virus, but antiserum to the Cooper-type and red deer herpesviruses did neutralize caprine virus to a limited extent.
在中和试验中，将牛疱疹病毒1（BHV - 1）分离株（库珀型毒株4975和牛津毒株）与牛疱疹病毒4（BHV - 4）分离株（85/16 TV）、马鹿疱疹病毒（D2839/1）和山羊疱疹病毒（E/CH）进行了比较。用兔制备了针对蚀斑选择病毒的超免疫抗血清，并进行了终点中和试验和动力学中和试验。BHV - 4与其他四种病毒明显不同。在这些试验中，密切相关的BHV - 1毒株也与马鹿疱疹病毒相关。牛津毒株在抗原性上似乎比库珀型毒株更接近马鹿疱疹病毒。山羊疱疹病毒抗血清不能中和任何一种BHV - 1毒株或马鹿病毒，但库珀型和马鹿疱疹病毒的抗血清在一定程度上能中和山羊病毒。
