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通过酶联免疫吸附测定法比较五种反刍动物α疱疹病毒之间的血清学关系。

A comparison of serological relationships among five ruminant alphaherpesviruses by ELISA.

作者信息

Lyaku J R, Nettleton P F, Marsden H

机构信息

Moredun Research Institute, Edinburgh, Scotland.

出版信息

Arch Virol. 1992;124(3-4):333-41. doi: 10.1007/BF01309813.

DOI:10.1007/BF01309813
PMID:1605741
Abstract

Using enzyme-linked immunosorbent assays the cross reactivity of bovine herpesvirus-1.1, bovine herpesvirus-1.2, caprine herpesvirus-2, cervine (red deer) herpesvirus-1 and rangiferine (reindeer) herpesvirus-1 has been examined using rabbit hyperimmune antisera and convalescent cattle and red deer field sera. Significant cross-reactivity among all the five viruses was demonstrated. A detailed analysis showed that: (1) the two bovine herpesviruses are most closely related, (2) the cervine, caprine and rangiferine viruses are more closely related to the bovine viruses than they are to each other, (3) the cervine herpesvirus is more related to the bovine herpesvirus than to the rangiferine or caprine herpesviruses and (4) the rangiferine virus is more related to the cervine virus than to the bovine and caprine viruses. Cattle and red deer sera reacted most strongly with the bovine and cervine viruses respectively.

摘要

利用酶联免疫吸附测定法,使用兔超免疫抗血清以及恢复期牛和马鹿的现场血清,检测了牛疱疹病毒1.1、牛疱疹病毒1.2、山羊疱疹病毒2、鹿(马鹿)疱疹病毒1和驯鹿疱疹病毒1的交叉反应性。结果表明,所有这五种病毒之间存在显著的交叉反应性。详细分析显示:(1)两种牛疱疹病毒关系最为密切;(2)鹿、山羊和驯鹿病毒与牛病毒的关系比它们彼此之间的关系更为密切;(3)鹿疱疹病毒与牛疱疹病毒的关系比与驯鹿或山羊疱疹病毒的关系更为密切;(4)驯鹿病毒与鹿病毒的关系比与牛和山羊病毒的关系更为密切。牛和马鹿血清分别与牛和鹿病毒反应最为强烈。

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