Deshpande Prasanna R, Khera Kanav, Thunga Girish, Hande Manjunath, Gouda Siddalingana T G, Nagappa Anantha Naik
Department of Pharmacy Practice, Manipal College of Pharmaceutical Sciences, Manipal University, Manipal, India.
J Pharmacol Pharmacother. 2011 Jan;2(1):40-2. doi: 10.4103/0976-500X.77114.
Atorvastatin-induced acute pancreatitis (AP) is one of the rare adverse effects available in the literature. We report a case of 53-year-old patient developed AP after treatment with atorvastatin monotherapy which resolved after drug withdrawal. Extensive workup on AP failed to reveal any other etiology for it. To our knowledge, this is one of the rare case reports of AP caused due to atorvastatin monotherapy and it further strengthens the fact that statins may cause AP. There is need of continued reporting of such a rare adverse effect of atorvastatin for increasing awareness and to manage and avoid the same.
阿托伐他汀所致急性胰腺炎(AP)是文献中记载的罕见不良反应之一。我们报告一例53岁患者,在接受阿托伐他汀单药治疗后发生急性胰腺炎,停药后病情缓解。对该例急性胰腺炎进行的全面检查未发现其他病因。据我们所知,这是阿托伐他汀单药治疗引起急性胰腺炎的罕见病例报告之一,进一步证实了他汀类药物可能导致急性胰腺炎这一事实。需要持续报告阿托伐他汀这种罕见的不良反应,以提高认识并加以处理和避免。