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多中心比较格拉斯哥 Blatchford 和 Rockall 评分在上消化道出血后临床终点的预测中的作用。

Multicentre comparison of the Glasgow Blatchford and Rockall Scores in the prediction of clinical end-points after upper gastrointestinal haemorrhage.

机构信息

Gastrointestinal unit, Glasgow Royal Infirmary, Glasgow, UK.

出版信息

Aliment Pharmacol Ther. 2011 Aug;34(4):470-5. doi: 10.1111/j.1365-2036.2011.04747.x. Epub 2011 Jun 26.

DOI:10.1111/j.1365-2036.2011.04747.x
PMID:21707681
Abstract

BACKGROUND

The Glasgow Blatchford Score (GBS) is increasingly being used to predict intervention and outcome following upper gastrointestinal haemorrhage (UGIH).

AIM

To compare the GBS with both the admission and full Rockall scores in predicting specific clinical end-points following UGIH.

PATIENTS AND METHODS

Data on consecutive patients presenting to four UK hospitals were collected. Admission history, clinical and laboratory data, endoscopic findings, treatment and clinical follow-up were recorded. Using ROC curves, we compared the three scores in the prediction of death, endoscopic or surgical intervention and transfusion. Results  A total of 1555 patients (mean age 56.7years) presented with UGIH during the study period. Seventy-four (4.8%) died, 223 (14.3%) had endoscopic or surgical intervention and 363 (23.3%) required transfusion. The GBS was similar at predicting death compared with both the admission Rockall (area under ROC curve 0.804 vs. 0.801) and full Rockall score (AUROC 0.741 vs. 0.790). In predicting endo-surgical intervention, the GBS was superior to the admission Rockall (AUROC 0.858 vs. 0.705; P<0.00005) and similar to the full Rockall score (AUROC 0.822 vs. 0.797). The GBS was superior to both admission Rockall (AUROC 0.944 vs. 0.756; P<0.00005) and full Rockall scores (AUROC 0.935 vs. 0.792; P<0.00005) in predicting need for transfusion.

CONCLUSIONS

Despite not incorporating age, the GBS is as effective as the admission and full Rockall scores in predicting death after UGIH. It is superior to both the admission and full Rockall scores in predicting need for transfusion, and superior to the admission Rockall score in predicting endoscopic or surgical intervention.

摘要

背景

格拉斯哥 Blatchford 评分(GBS)越来越多地用于预测上消化道出血(UGIH)后的干预和结果。

目的

比较 GBS 与入院 Rockall 评分和完整 Rockall 评分在预测 UGIH 后特定临床终点方面的表现。

患者和方法

收集了四家英国医院连续就诊的患者数据。记录入院病史、临床和实验室数据、内镜检查结果、治疗和临床随访。我们使用 ROC 曲线比较了这三种评分在预测死亡、内镜或手术干预和输血方面的表现。结果:研究期间共有 1555 例(平均年龄 56.7 岁)患者出现 UGIH。74 例(4.8%)死亡,223 例(14.3%)进行了内镜或手术干预,363 例(23.3%)需要输血。GBS 在预测死亡方面与入院 Rockall 评分(ROC 曲线下面积 0.804 与 0.801)和完整 Rockall 评分(AUROC 0.741 与 0.790)相似。在预测内镜或手术干预方面,GBS 优于入院 Rockall 评分(AUROC 0.858 与 0.705;P<0.00005),与完整 Rockall 评分相当(AUROC 0.822 与 0.797)。GBS 在预测输血需求方面优于入院 Rockall 评分(AUROC 0.944 与 0.756;P<0.00005)和完整 Rockall 评分(AUROC 0.935 与 0.792;P<0.00005)。

结论

尽管没有纳入年龄因素,GBS 与入院和完整 Rockall 评分在预测 UGIH 后死亡方面同样有效。它在预测输血需求方面优于入院和完整 Rockall 评分,在预测内镜或手术干预方面优于入院 Rockall 评分。

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