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DIPOS:水稻相互作用蛋白质数据库。

DIPOS: database of interacting proteins in Oryza sativa.

作者信息

Sapkota Achyut, Liu Xiaoping, Zhao Xing-Ming, Cao Yongwei, Liu Jingdong, Liu Zhi-Ping, Chen Luonan

机构信息

Institute of Systems Biology, Shanghai University, Shanghai 200444, China.

出版信息

Mol Biosyst. 2011 Sep;7(9):2615-21. doi: 10.1039/c1mb05120b. Epub 2011 Jun 29.

Abstract

Rice is an important crop throughout the world and is the staple food for about half the world's population. For better breeding and improved production, we need to know the function of rice molecules which facilitate their function through interactions with each other. The database of interacting proteins in Oryza sativa (DIPOS) provides comprehensive information of interacting proteins in rice, where the interactions are predicted using two computational methods, i.e., interologs and domain based methods. DIPOS contains 14 614 067 pairwise interactions among 27 746 proteins, covering about 41% of the whole Oryaza sativa proteome. Furthermore, each interaction is assigned a confidence score which further enables biologists to sort out the important proteins. Biological explanations of pathways and interactions are also provided based on the database. Public access to the DIPOS is available at and .

摘要

水稻是全球重要的农作物,是世界约一半人口的主食。为了更好地进行育种和提高产量,我们需要了解水稻分子的功能,这些分子通过相互作用来发挥其功能。水稻互作蛋白数据库(DIPOS)提供了水稻互作蛋白的全面信息,其中的相互作用是使用两种计算方法预测的,即同源互作和基于结构域的方法。DIPOS包含27746个蛋白质之间的14614067对相互作用,覆盖了整个水稻蛋白质组的约41%。此外,每个相互作用都被赋予一个置信度分数,这进一步使生物学家能够筛选出重要的蛋白质。该数据库还提供了对途径和相互作用的生物学解释。可通过……公开访问DIPOS。 (注:原文中“at and”表述不完整,未明确具体网址等信息)

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