[Virus-neutralizing activity of colostral immunoglobulins in swine vaccinated with an inactivated vaccine against Aujeszky's disease virus].

Colostral globulins of sows immunized with an ethanol-saponin vaccine against Aujeszky's disease virus were fractionated through gel filtration by means of Sephadex-200. The virus-neutralizing activity of the globulin fractions identified through agar gel immunoelectrophoresis was evaluated by the virus-neutralizing test with cell cultures. The level of the antibodies found in class IgG substantially exceeded that of the IgA antibodies. It is believed that after muscular application of an ethanolsaponin vaccine against Aujeszky's disease the mammary gland of the vaccinated sows secretes virus-neutralizing antibodies mainly of the IgG class.