Key Lab of Chemical Safety and Health, National Institute of Nutrition and Food Safety, Chinese Center for Disease Control and Prevention, No. 7, Panjiayuan nanli Road, Chaoyang District, Beijing 100021, PR China.
Environ Int. 2012 Jul;42:152-9. doi: 10.1016/j.envint.2011.05.018. Epub 2011 Jun 28.
Dietary exposure to persistent organochlorine pesticides (OCPs) was assessed for Chinese populations, using the total diet study (TDS) approach in 2007. Multistage random cluster sampling method was used in this study. 108 composite samples, representative of foods "as consumed" by the Chinese were analyzed for residues of OCPs by a multi-residue method. The result showed that hexachlorobenzene (HCB), dichloro-diphenyl-trichloroethane (DDT), chlordane compounds (CHLs), hexachlorocyclohexane (HCH) and heptachlor could be detected in, respectively 84%, 39%, 37%, 13% and 5% of all samples. Concentrations of DDT in all samples ranged from undetectable levels to 72.2 μg/kg. Others were minor components in the OCPs profile. The residual levels of OCPs were significantly below the Extraneous Maximum Residue Limits (EMRLs). Based on the 2000 nationwide food consumption survey, the average dietary exposure of the Chinese to DDT, HCH, HCB, CHLs, and heptachlor was estimated to be 0.016, 0.002, 0.009, 0.006, and 0.001 μg/kg body weight per day respectively, showing a significant decrease trend compared with the past. The major food groups contributing to dietary OCPs were aquatic foods, meats, and cereals. The average and high end estimated daily intakes of different OCPs for the Chinese were both lower than the tolerable daily intake (TDI) suggested by authorities indicating low health risk of OCPs dietary exposure among Chinese adults at present. However, the risk of carcinogenicity of the OCPs should be concerned with if the carcinogenicity effects from the exposures to these OCPs were considered.
2007 年，采用总膳食研究（TDS）方法对中国人的持久性有机氯农药（OCPs）膳食暴露进行了评估。本研究采用多阶段随机聚类抽样方法。对 108 个复合样本进行了多残留分析方法分析，这些样本代表中国人消费的食物。结果表明，在所有样本中分别有 84%、39%、37%、13%和 5%可以检测到六氯苯（HCB）、滴滴涕（DDT）、氯丹化合物（CHLs）、六氯环己烷（HCH）和七氯。所有样品中 DDT 的浓度均低于检测限至 72.2μg/kg。其他均为 OCPs 谱中的次要成分。OCPs 的残留水平明显低于外来最大残留限量（EMRLs）。基于 2000 年全国食物消费调查，中国人对 DDT、HCH、HCB、CHLs 和七氯的平均膳食暴露估计分别为 0.016、0.002、0.009、0.006 和 0.001μg/kg 体重/天，与过去相比呈显著下降趋势。对膳食 OCPs 贡献最大的食物组是水产食品、肉类和谷物。不同 OCPs 的平均和高估计日摄入量均低于有关部门建议的可耐受日摄入量（TDI），表明目前中国成年人的 OCPs 膳食暴露的健康风险较低。然而，如果考虑到这些 OCPs 的暴露致癌效应，则应关注 OCPs 的致癌性风险。
