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利多卡因贴剂在经皮内镜腰椎间盘切除术的应用。

Use of lidocaine patch for percutaneous endoscopic lumbar discectomy.

机构信息

Department of Anesthesia and Pain Medicine, School of Medicine, Pusan National University, Yangsan, Korea.

出版信息

Korean J Pain. 2011 Jun;24(2):74-80. doi: 10.3344/kjp.2011.24.2.74. Epub 2011 Jun 3.

Abstract

BACKGROUND

Lidocaine patch (L5P) has demonstrated short-term efficacy in treating both acute surgical pain and chronic neuropathic pain with tolerable side effects. Percutaneous endoscopic lumbar discectomy (PELD) is the mainstay of minimally invasive spine surgery (MISS). Sufficient analgesia during PELD surgery makes the patient consider it real MISS. This study was performed to evaluate the efficacy and adverse effects of lidocaine patch in patients who underwent PELD under local anesthesia.

METHODS

L5P (L group) or placebo (P group) was randomly applied on the skin of the back covering the anticipated path of the working channel before 1 hour of surgery in 100 patients who underwent a single level PELD at L4-L5. Efficacy of the lidocaine patch was assessed by patient's numeric rating scale (NRS) of pain at each stage during the surgery and by a 5-scale grading of the satisfaction with the anesthesia of the operator and patients after surgery.

RESULTS

Mean NRS scores at the stages of needle insertion, skin incision, serial dilation and insertion of working channel, and subcutaneous suture were significantly lower in the L group than the P group. Postoperative operator's and patients' satisfaction scores were also significantly higher in L group than in the P group. There were subtle adverse effects in both groups.

CONCLUSIONS

L5P provided better pain relief during PELD, especially at the stage of needle insertion, skin incision, serial dilation and insertion of working channel, and subcutaneous suture. It also provided higher patient and operator postoperative satisfaction, with only subtle adverse effects.

摘要

背景

利多卡因贴剂(L5P)在治疗急性手术疼痛和慢性神经病理性疼痛方面具有短期疗效,且副作用可耐受。经皮内镜腰椎间盘切除术(PELD)是微创脊柱手术(MISS)的主要方法。PELD 手术过程中充分的镇痛可使患者认为其真正微创。本研究旨在评估利多卡因贴剂在局部麻醉下接受 PELD 手术的患者中的疗效和不良反应。

方法

在 100 例行单节段 L4-L5 PELD 的患者中,于手术前 1 小时在背部皮肤(预计工作通道路径)上随机应用 L5P(L 组)或安慰剂(P 组)。通过患者在手术过程中各阶段的数字评分量表(NRS)评估利多卡因贴剂的疗效,并通过手术结束后操作员和患者对麻醉的 5 级评分评估满意度。

结果

与 P 组相比,L 组在针插入、皮肤切开、连续扩张和工作通道插入以及皮下缝合等阶段的 NRS 评分均显著降低。L 组术后操作员和患者的满意度评分也明显高于 P 组。两组均有轻微不良反应。

结论

L5P 在 PELD 过程中提供了更好的镇痛效果,特别是在针插入、皮肤切开、连续扩张和工作通道插入以及皮下缝合阶段。它还提供了更高的患者和操作员术后满意度,仅有轻微的不良反应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0abb/3111563/436482045fa0/kjpain-24-74-g001.jpg

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