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心肾综合征中的心脏再同步治疗

Cardiac resynchronization therapy in the cardiorenal syndrome.

作者信息

Davis Margot K, Virani Sean A

机构信息

Division of Cardiology, Gordon and Leslie Diamond Health Care Centre, The University of British Columbia, Vancouver, BC, Canada V5Z 1M9.

出版信息

Int J Nephrol. 2011;2011:168461. doi: 10.4061/2011/168461. Epub 2011 Jun 9.

DOI:10.4061/2011/168461
PMID:21716684
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3118524/
Abstract

The cardiorenal syndrome (CRS) is a complex clinical syndrome in which dysfunction of either the heart or the kidneys affects the functioning of the other organ system. Many therapies used in heart failure have further detrimental effects on renal function. Cardiac resynchronization therapy (CRT) is a relatively new form of device therapy that reduces morbidity and mortality in patients with heart failure. This review will discuss the effects of CRT on renal function in patients with CRS, the impact of baseline renal function on response to CRT, and potential risks associated with CRT in this unique population.

摘要

心肾综合征（CRS）是一种复杂的临床综合征，其中心脏或肾脏的功能障碍会影响另一个器官系统的功能。许多用于治疗心力衰竭的疗法对肾功能有进一步的不利影响。心脏再同步治疗（CRT）是一种相对较新的器械治疗形式，可降低心力衰竭患者的发病率和死亡率。本综述将讨论CRT对CRS患者肾功能的影响、基线肾功能对CRT反应的影响以及在这一特殊人群中与CRT相关的潜在风险。

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引用本文的文献

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Chronic Heart Failure and Comorbid Renal Dysfunction - A Focus on Type 2 Cardiorenal Syndrome.慢性心力衰竭与合并的肾功能不全——聚焦于2型心肾综合征
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本文引用的文献

1
Cardiorenal syndrome: new perspectives.心肾综合征：新视角
Circulation. 2010 Jun 15;121(23):2592-600. doi: 10.1161/CIRCULATIONAHA.109.886473.
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Response to cardiac resynchronization therapy in patients with heart failure and renal insufficiency.心力衰竭合并肾功能不全患者对心脏再同步治疗的反应
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Effects of cardiac resynchronization therapy on systemic inflammation and neurohormonal pathways in heart failure.心脏再同步治疗对心力衰竭患者全身炎症和神经激素途径的影响。
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5
Importance of venous congestion for worsening of renal function in advanced decompensated heart failure.静脉淤血在晚期失代偿性心力衰竭中对肾功能恶化的重要性。
J Am Coll Cardiol. 2009 Feb 17;53(7):589-596. doi: 10.1016/j.jacc.2008.05.068.
6
Increased central venous pressure is associated with impaired renal function and mortality in a broad spectrum of patients with cardiovascular disease.在广泛的心血管疾病患者中，中心静脉压升高与肾功能受损及死亡率相关。
J Am Coll Cardiol. 2009 Feb 17;53(7):582-588. doi: 10.1016/j.jacc.2008.08.080.
7
Cardiorenal syndrome.心肾综合征
J Am Coll Cardiol. 2008 Nov 4;52(19):1527-39. doi: 10.1016/j.jacc.2008.07.051.
8
Preservation of renal function in response to cardiac resynchronization therapy.
Circ J. 2008 Nov;72(11):1794-9. doi: 10.1253/circj.cj-08-0424. Epub 2008 Oct 7.
9
ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2008: the Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2008 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association of the ESC (HFA) and endorsed by the European Society of Intensive Care Medicine (ESICM).《2008年欧洲心脏病学会急性和慢性心力衰竭诊断与治疗指南》：欧洲心脏病学会2008年急性和慢性心力衰竭诊断与治疗特别工作组制定。与欧洲心脏病学会心力衰竭协会（HFA）合作编写，并得到欧洲重症医学学会（ESICM）认可。
Eur Heart J. 2008 Oct;29(19):2388-442. doi: 10.1093/eurheartj/ehn309. Epub 2008 Sep 17.
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Cardiac resynchronization therapy improves renal function in human heart failure with reduced glomerular filtration rate.心脏再同步治疗可改善肾小球滤过率降低的人类心力衰竭患者的肾功能。
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