拉丁美洲子宫颈浸润癌的危险因素。
Risk factors for invasive carcinoma of the uterine cervix in Latin America.
作者信息
Herrero R, Brinton L A, Reeves W C, Brenes M M, Tenorio F, de Britton R C, Gaitán E, Montalván P, García M, Rawls W E
机构信息
Environmental Epidemiology Branch, National Cancer Institute, Bethesda, MD 20892.
出版信息
Bull Pan Am Health Organ. 1990;24(3):263-83.
A study of 759 cervical cancer patients, 1,430 controls, and 689 sex partners in four Latin American countries has made it possible to assess the influence of multiple factors upon the risk of invasive cervical cancer. The principal risk factors identified were the woman's age at first coitus, the number of her steady sex partners, her number of live births, the presence of DNA from human papillomavirus (HPV) types 16 or 18, a history of venereal disease, nonparticipation in early detection programs, and low socioeconomic status. There is good reason to believe that extensive detection programs directed mainly at high-risk groups in the Americas can reduce the high incidence of cervical cancer in this Region.
一项针对四个拉丁美洲国家的759名宫颈癌患者、1430名对照者及689名性伴侣的研究，使得评估多种因素对浸润性宫颈癌风险的影响成为可能。确定的主要风险因素包括女性首次性交的年龄、其固定性伴侣的数量、活产数、16型或18型人乳头瘤病毒（HPV）DNA的存在、性病病史、未参与早期检测项目以及社会经济地位低下。有充分理由相信，主要针对美洲高危人群的广泛检测项目能够降低该地区宫颈癌的高发病率。
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