兆赫兹条纹模式傅里叶域光学相干断层扫描。
Megahertz streak-mode Fourier domain optical coherence tomography.
机构信息
Clemson University, Department of Bioengineering, COMSET, Clemson, South Carolina 29634, USA.
出版信息
J Biomed Opt. 2011 Jun;16(6):066016. doi: 10.1117/1.3593149.
Abstract
Here we present an ultrahigh-speed Fourier-domain optical coherence tomography (OCT) that records the OCT spectrum in streak mode with a high-speed area scan camera, which allows higher OCT imaging speed than can be achieved with a line-scan camera. Unlike parallel OCT techniques that also use area scan cameras, the conventional single-mode fiber-based point-scanning mechanism is retained to provide a confocal gate that rejects multiply scattered photons from the sample. When using a 1000 Hz resonant scanner as the streak scanner, 1,016,000 A-scans have been obtained in 1 s. This method's effectiveness has been demonstrated by recording in vivo OCT-image sequences of embryonic chick hearts at 1000 frames/s. In addition, 2-megahertz OCT data have been obtained with another high speed camera.
摘要
我们在此介绍一种超高速傅里叶域光学相干断层扫描（OCT）系统，该系统使用高速面阵相机以条纹模式记录 OCT 光谱，从而实现比线扫描相机更高的 OCT 成像速度。与也使用面阵相机的并行 OCT 技术不同，该系统保留了传统的单模光纤点扫描机制，以提供共聚焦门，从而从样品中排除多次散射的光子。当使用 1000 Hz 共振扫描仪作为条纹扫描仪时，在 1 秒内获得了 1,016,000 个 A 扫描。通过以 1000 帧/秒的速度记录胚胎鸡心脏的体内 OCT 图像序列，验证了该方法的有效性。此外，还使用另一台高速相机获得了 2 兆赫兹的 OCT 数据。
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本文引用的文献
1
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J Biomed Opt. 1998 Jan;3(1):21-31. doi: 10.1117/1.429899.
2
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Opt Express. 2010 Jul 5;18(14):14685-704. doi: 10.1364/OE.18.014685.
3
Crosstalk rejection in parallel optical coherence tomography using spatially incoherent illumination with partially coherent sources.使用部分相干光源的空间非相干照明进行并行光学相干断层扫描中的串扰抑制。
Opt Lett. 2010 Jul 1;35(13):2305-7. doi: 10.1364/OL.35.002305.
4
Parallel Fourier domain optical coherence tomography for in vivo measurement of the human eye.用于人眼活体测量的并行傅里叶域光学相干断层扫描技术。
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Motion artifacts in optical coherence tomography with frequency-domain ranging.频域测距光学相干断层扫描中的运动伪影。
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8
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10
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