Department of Gynecology and Obstetrics, Emory University, Atlanta, Georgia 30312, USA.
Fertil Steril. 2011 Sep;96(3):546-53. doi: 10.1016/j.fertnstert.2011.05.094. Epub 2011 Jun 30.
To review the effects of human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) in terms of its associated comorbid conditions and the side effects of antiretroviral treatment on fertility.
PubMed computer search to identify relevant articles.
Research institution.
PATIENT(S): None.
INTERVENTION(S): None.
MAIN OUTCOME MEASURE(S): None.
RESULT(S): Biological alterations in reproductive physiology may account for subfertility in patients infected with HIV. Psychosocial factors in patients with HIV infection may affect their reproductive desires and outcomes. Antiretroviral medications may have direct toxicity on gametes and embryos. Available evidence indicates that fertility treatments can be a safe option for couples with HIV-discordant infection status, although the potential risk of viral transmission cannot be completely eliminated.
CONCLUSION(S): Because their potential reproductive desires are increasingly becoming a concern in the health care of young HIV-infected patients, additional data are needed to address the effect of HIV and its treatments on their fertility and reproductive outcomes.
综述人类免疫缺陷病毒/获得性免疫缺陷综合征（HIV/AIDS）相关合并症及其对生育的影响，以及抗逆转录病毒治疗的副作用。
利用 PubMed 计算机检索，以确定相关文章。
研究机构。
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生殖生理学的生物学改变可能导致 HIV 感染患者的生育能力下降。HIV 感染者的心理社会因素可能会影响他们的生育愿望和结果。抗逆转录病毒药物可能对配子和胚胎有直接毒性。现有证据表明，对于 HIV 不一致感染状态的夫妇来说，生育治疗是一种安全的选择，尽管不能完全消除病毒传播的潜在风险。
由于他们潜在的生育愿望越来越成为年轻 HIV 感染患者医疗保健的关注点，因此需要更多的数据来解决 HIV 及其治疗对其生育能力和生殖结果的影响。
