Key Laboratory of Chemical Safety and Health, National Institute of Nutrition and Food Safety, Chinese Center for Disease Control and Prevention, 29 Nanwei Road, Beijing 100050, China.
Chemosphere. 2011 Sep;85(2):156-62. doi: 10.1016/j.chemosphere.2011.06.038. Epub 2011 Jul 2.
Perfluorinated compounds (PFCs) including perfluorooctanoate (PFOA) and perfluorooctane sulfonate (PFOS) have been used in a wide range of industrial and consumer applications since 1960s. The previous studies have reported the occurrences of PFOS and PFOA in human blood and serum from various countries. In this study, 141 human whole blood samples collected from four cities around Bohai Sea in China including Qinhuangdao, Tangshan, Weihai, and Zouping were analyzed for PFCs. The highest median concentration of total PFCs was found in whole blood samples from Tangshan (14.01 ng mL(-1)). The median concentration of total PFCs in samples from Zouping (7.28 ng mL(-1)) was the lowest, but the median concentration of PFOA (3.26 ng mL(-1)) was the highest among four cities and the percentage proportion of PFOA (45%) was higher than that of PFOS (30%). Based on the different profiles of PFCs between coastal cities, it was suggested that there might be different human exposure sources and pathways of PFCs around Bohai Sea.
全氟化合物（PFCs）包括全氟辛酸（PFOA）和全氟辛烷磺酸（PFOS）自 20 世纪 60 年代以来被广泛应用于工业和消费领域。先前的研究报告了来自不同国家的人类血液和血清中 PFOS 和 PFOA 的存在。本研究分析了来自中国渤海湾周边四个城市（秦皇岛、唐山、威海和邹平）的 141 个人全血样本中的 PFCs。全血样本中总 PFCs 的最高中位数浓度出现在唐山（14.01ng/mL）。来自邹平的样本中总 PFCs 的中位数浓度（7.28ng/mL）最低，但 PFOA（3.26ng/mL）的中位数浓度在四个城市中最高，且 PFOA（45%）的比例高于 PFOS（30%）。基于沿海城市之间 PFCs 的不同分布情况，表明渤海湾周边可能存在不同的 PFCs 人体暴露源和途径。
