Palumbo P J, Elveback L R, Whisnant J P
Adv Neurol. 1978;19:593-601.
The incidence of TIA, stroke, and neuropathy was studied in a community-based maturity-onset diabetic population. The frequencies of TIA and stroke were increased in maturity-onset diabetic patients as compared to the population of Rochester, Minnesota. The median age of occurrence of TIA and stroke in diabetics was 74 years, not significantly different from that in non-diabetics. Diabetic patients with hypertension at the time of diagnosis of diabetes mellitus had an increased frequency of TIA and stroke. Control of hypertension and/or diabetes mellitus was associated with a decreased frequency of TIA or stroke. Obesity, clinical coronary heart disease, and an abnormal electrocardiogram at the time of diagnosis of diabetes mellitus were not associated with a significantly increased frequency of TIA or stroke. The most common type of peripheral neuropathy in diabetes mellitus was distal polyneuropathy. Mononeuropathy and autonomic neuropathy were much less frequent. The frequency of distal polyneuropathy increased with the duration of diabetes mellitus. The frequency of neuropathy was increased in patients with poor control, reemphasizing the importance of diabetic control in the prevention of diabetic complications.
在一个以社区为基础的成年发病型糖尿病患者群体中，研究了短暂性脑缺血发作（TIA）、中风和神经病变的发病率。与明尼苏达州罗切斯特市的人群相比，成年发病型糖尿病患者中TIA和中风的发生率有所增加。糖尿病患者发生TIA和中风的中位年龄为74岁，与非糖尿病患者无显著差异。在诊断糖尿病时患有高血压的糖尿病患者，TIA和中风的发生率增加。控制高血压和/或糖尿病与TIA或中风发生率降低相关。在诊断糖尿病时，肥胖、临床冠心病和心电图异常与TIA或中风发生率显著增加无关。糖尿病中最常见的周围神经病变类型是远端多发性神经病变。单神经病变和自主神经病变则要少见得多。远端多发性神经病变的发生率随糖尿病病程延长而增加。血糖控制不佳的患者神经病变发生率增加，再次强调了糖尿病控制在预防糖尿病并发症中的重要性。
