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Increased levels of total tau protein in the cerebrospinal fluid in Huntington's disease.

作者信息

Constantinescu Radu, Romer Megan, Zetterberg Henrik, Rosengren Lars, Kieburtz Karl

出版信息

Parkinsonism Relat Disord. 2011 Nov;17(9):714-5. doi: 10.1016/j.parkreldis.2011.06.010. Epub 2011 Jul 5.

DOI:10.1016/j.parkreldis.2011.06.010
PMID:21733739
Abstract
摘要

相似文献

1
Increased levels of total tau protein in the cerebrospinal fluid in Huntington's disease.亨廷顿舞蹈症患者脑脊液中总tau蛋白水平升高。
Parkinsonism Relat Disord. 2011 Nov;17(9):714-5. doi: 10.1016/j.parkreldis.2011.06.010. Epub 2011 Jul 5.
2
Is there a role of Tau in Huntington's disease?Tau蛋白在亨廷顿舞蹈症中起作用吗?
J Neurochem. 2016 Oct;139(1):9-10. doi: 10.1111/jnc.13762. Epub 2016 Sep 21.
3
Cerebrospinal fluid total tau concentration predicts clinical phenotype in Huntington's disease.脑脊液总tau蛋白浓度可预测亨廷顿舞蹈病的临床表型。
J Neurochem. 2016 Oct;139(1):22-5. doi: 10.1111/jnc.13719. Epub 2016 Sep 20.
4
Cerebrospinal fluid levels of quinolinic acid in Huntington's disease and schizophrenia.
Ann Neurol. 1988 Oct;24(4):580-2. doi: 10.1002/ana.410240417.
5
Levels of the light subunit of neurofilament triplet protein in cerebrospinal fluid in Huntington's disease.亨廷顿病患者脑脊液中神经丝三联蛋白轻链亚基水平
Parkinsonism Relat Disord. 2009 Mar;15(3):245-8. doi: 10.1016/j.parkreldis.2008.05.012. Epub 2008 Dec 4.
6
Normal hypocretin-1 (orexin-A) levels in the cerebrospinal fluid of patients with Huntington's disease.亨廷顿舞蹈症患者脑脊液中正常的下丘脑分泌素-1(食欲素-A)水平。
Brain Res. 2005 Nov 30;1063(2):201-3. doi: 10.1016/j.brainres.2005.09.028. Epub 2005 Nov 2.
7
[Cerebrospinal fluid metabolism of biogenic amines in Huntington chorea].[亨廷顿舞蹈病中生物胺的脑脊液代谢]
Schweiz Arch Neurol Neurochir Psychiatr. 1976;119(2):333-42.
8
[Free aminoacids concentration in the plasma, red cell hemolysates and cerebrospinal fluid of patients with Huntington's chorea (author's transl)].
Przegl Lek. 1975;32(11):796-802.
9
[Serum and csf proteins in Huntington's chorea].
Med Arh. 1974 May-Jun;28(3):313-8.
10
Assessment of cerebrospinal fluid (CSF) beta-amyloid (1-42), phosphorylated tau (ptau-181) and total Tau protein in patients with Alzheimer's disease (AD) and other dementia at Siriraj Hospital, Thailand.泰国诗里拉吉医院对阿尔茨海默病(AD)及其他痴呆症患者的脑脊液(CSF)β-淀粉样蛋白(1-42)、磷酸化tau蛋白(ptau-181)和总tau蛋白进行评估。
J Med Assoc Thai. 2011 Feb;94 Suppl 1:S77-83.

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A 14-Year Study of Serum Glial Fibrillary Acidic Protein and Total Tau in Premanifest Huntington's.一项针对前驱期亨廷顿病患者血清胶质纤维酸性蛋白和总tau蛋白的14年研究。
Ann Clin Transl Neurol. 2025 Jun;12(6):1296-1301. doi: 10.1002/acn3.70057. Epub 2025 Apr 21.
2
Tau levels in platelets isolated from Huntington's disease patients serve as a biomarker of disease severity.从亨廷顿舞蹈症患者中分离出的血小板中的tau蛋白水平可作为疾病严重程度的生物标志物。
J Neurol. 2025 Mar 6;272(3):254. doi: 10.1007/s00415-025-12966-9.
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Elevated plasma and CSF neurofilament light chain concentrations are stabilized in response to mutant huntingtin lowering in the brains of Huntington's disease mice.
血浆和脑脊液神经丝轻链浓度升高在亨廷顿病小鼠的大脑中响应于突变亨廷顿蛋白降低而稳定。
Transl Neurodegener. 2024 Oct 8;13(1):50. doi: 10.1186/s40035-024-00443-8.
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Cognitive phenotype and neurodegeneration associated with Tau in Huntington's disease.与亨廷顿病中的 Tau 相关的认知表型和神经退行性变。
Ann Clin Transl Neurol. 2024 May;11(5):1160-1171. doi: 10.1002/acn3.52031. Epub 2024 Mar 27.
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Tau: a biomarker of Huntington's disease.tau:亨廷顿病的生物标志物。
Mol Psychiatry. 2023 Oct;28(10):4070-4083. doi: 10.1038/s41380-023-02230-9. Epub 2023 Sep 25.
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Age-Dependent Increase in Tau Phosphorylation at Serine 396 in Huntington's Disease Prefrontal Cortex.亨廷顿病前额皮质中丝氨酸 396 处 tau 磷酸化的年龄依赖性增加。
J Huntingtons Dis. 2023;12(3):267-281. doi: 10.3233/JHD-230588.
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Study protocol of IMAGINE-HD: Imaging iron accumulation and neuroinflammation with 7T-MRI + CSF in Huntington's disease.亨廷顿病患者的 7T-MRI+CSF 成像:铁沉积与神经炎症研究方案。
Neuroimage Clin. 2023;39:103450. doi: 10.1016/j.nicl.2023.103450. Epub 2023 Jun 8.
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Implications of Tau Dysregulation in Huntington's Disease and Potential for New Therapeutics.tau 失调在亨廷顿病中的意义及新疗法的潜力
J Huntingtons Dis. 2023;12(1):1-13. doi: 10.3233/JHD-230569.
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Targeting Tau to Treat Clinical Features of Huntington's Disease.靶向Tau蛋白治疗亨廷顿舞蹈症的临床症状
Front Neurol. 2020 Nov 19;11:580732. doi: 10.3389/fneur.2020.580732. eCollection 2020.
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Mutant Huntingtin Is Cleared from the Brain via Active Mechanisms in Huntington Disease.亨廷顿病中通过主动机制清除脑中的突变亨廷顿蛋白。
J Neurosci. 2021 Jan 27;41(4):780-796. doi: 10.1523/JNEUROSCI.1865-20.2020. Epub 2020 Dec 11.