Laboratorio de Virología, Departamento de Infectología, Hospital Infantil de México Federico Gómez, México, México.
Intervirology. 2012;55(4):318-20. doi: 10.1159/000328665. Epub 2011 Jul 5.
We used nested multiplex polymerase chain reaction to determine the distribution of cytomegalovirus gB genotype in 30 Mexican children undergoing bone marrow transplantation. The genotypes were: gB1, 9/30 (30%); gB2, 8/30 (27%); gB3, 4/30 (13%), and gB4, 1/30 (3%); mixed genotypes were identified in 8/30 patients (27%). We conclude that the predominant genotypes identified were gB2 and gB1. The gB5 genotype was not detected, and a high proportion of mixed genotype was found.
我们使用巢式多重聚合酶链反应来确定 30 名接受骨髓移植的墨西哥儿童中巨细胞病毒 gB 基因型的分布。基因型为：gB1，9/30（30%）；gB2，8/30（27%）；gB3，4/30（13%）和 gB4，1/30（3%）；8/30 名患者（27%）中存在混合基因型。我们得出结论，确定的主要基因型是 gB2 和 gB1。未检测到 gB5 基因型，并且发现了很高比例的混合基因型。
