维甲酸可促进血小板衍生生长因子α受体基因的转录。
Retinoic acid promotes transcription of the platelet-derived growth factor alpha-receptor gene.
作者信息
Wang C, Kelly J, Bowen-Pope D F, Stiles C D
机构信息
Department of Microbiology and Molecular Genetics, Harvard Medical School, Boston, Massachusetts 02115.
出版信息
Mol Cell Biol. 1990 Dec;10(12):6781-4. doi: 10.1128/mcb.10.12.6781-6784.1990.
Abstract
Retinoic acid together with dibutyryl cyclic AMP stimulated transcription of the platelet-derived growth factor alpha-receptor gene in embryonal carcinoma cells (line F9). Processed mRNA transcripts appeared within 4 h after exposure to these agents, and functional alpha:alpha homodimers appeared within 24 h.
摘要
视黄酸与二丁酰环磷酸腺苷一起刺激胚胎癌细胞（F9细胞系）中血小板衍生生长因子α受体基因的转录。在接触这些试剂后4小时内出现加工后的mRNA转录本，24小时内出现功能性α:α同二聚体。
Zotero 插件