University of Plymouth, Drake Circus, Plymouth, PL4 8AA, UK.
Sci Total Environ. 2011 Sep 1;409(19):3628-33. doi: 10.1016/j.scitotenv.2011.06.011. Epub 2011 Jul 13.
During 2001 to 2004, a study was conducted to assess the indoor environmental and health impact of installing allergen-reducing interventions in the homes of asthmatic children. Based on the results of a pilot study, to determine an intervention that would provide improved symptom scores and a reduction in house dust mite allergen (Der p 1), mechanical ventilation and heat recovery (MVHR) systems were installed in 16 homes. Environmental and respiratory health assessments were conducted before and after the installation of the MVHR systems. The results indicated that the installation of MVHR systems reduced Der p 1 concentrations in living room carpets and mattresses. There were significant reductions in symptom scores for breathlessness during exercise, wheezing, and coughing during the day and night. Although, there was not a parallel control group for the main study, the lack of change in the pilot study control group (who did not receive an intervention), indicated that the changes in symptom scores were in part to do with the intervention. Larger scale trials are needed to determine the efficacy of MVHR systems in homes to improve indoor air quality and reduce asthma symptoms.
2001 年至 2004 年期间，一项研究旨在评估在哮喘儿童的家庭中安装过敏原减少干预措施对室内环境和健康的影响。基于初步研究的结果，为了确定一种能够提高症状评分并减少屋尘螨过敏原（Der p 1）的干预措施，在 16 个家庭中安装了机械通风和热回收（MVHR）系统。在安装 MVHR 系统前后进行了环境和呼吸健康评估。结果表明，安装 MVHR 系统降低了客厅地毯和床垫中的 Der p 1 浓度。运动时呼吸困难、喘息和夜间咳嗽的症状评分有显著降低。尽管主要研究没有平行对照组，但初步研究对照组（未接受干预）没有变化，表明症状评分的变化部分与干预有关。需要更大规模的试验来确定 MVHR 系统在改善室内空气质量和减轻哮喘症状方面在家中的疗效。
