Faculdade de Farmácia, Universidade Federal do Rio Grande do Sul, Av. Ipiranga 2752, 90610.000, Porto Alegre, RS, Brazil.
Trans R Soc Trop Med Hyg. 2011 Oct;105(10):604-6. doi: 10.1016/j.trstmh.2011.06.002. Epub 2011 Jul 13.
Correct diagnosis of parasitic infections is essential for the treatment of individuals avoiding indiscriminate use of anthelmintics which increases drug resistance. In a comparative study between the spontaneous sedimentation technique and Paratest(®), 140 stool samples were analyzed for the detection of parasites. The prevalence was 12.7% obtained by the spontaneous sedimentation method but only 5.7% using Paratest(®). Paratest(®) has shown a high proportion of false-negative results, lower sensitivity and negative predictive values compared with the spontaneous sedimentation method. Further optimization and studies of the Paratest(®) method are necessary for wider use in clinical diagnosis.
正确诊断寄生虫感染对于治疗个体至关重要，可以避免盲目使用驱虫药，从而减少药物耐药性的产生。在自然沉淀法和 Paratest(®)之间的对比研究中，分析了 140 份粪便样本以检测寄生虫。自然沉淀法的检出率为 12.7%，而 Paratest(®)仅为 5.7%。与自然沉淀法相比，Paratest(®)显示出高比例的假阴性结果，较低的敏感性和阴性预测值。需要对 Paratest(®)方法进行进一步的优化和研究，以使其更广泛地应用于临床诊断。
