Göttingen Genomics Laboratory, Institute of Microbiology and Genetics, Georg-August University Göttingen, Grisebachstr. 8, D-37077 Göttingen, Germany.
J Bacteriol. 2011 Sep;193(18):5017. doi: 10.1128/JB.05660-11. Epub 2011 Jul 8.
Here we announce the complete genome sequence of the copper-resistant bacterium Cupriavidus necator N-1, the type strain of the genus Cupriavidus. The genome consists of two chromosomes and two circular plasmids. Based on genome comparison, the chromosomes of C. necator N-1 share a high degree of similarity with the two chromosomal replicons of the bioplastic-producing hydrogen bacterium Ralstonia eutropha H16. The two strains differ in their plasmids and the presence of hydrogenase genes, which are absent in strain N-1.
我们在此宣布,耐铜菌 Cupriavidus necator N-1 的全基因组序列被成功解析,该菌是 Cupriavidus 属的模式种。基因组由两条染色体和两个环状质粒组成。基于基因组比较,C. necator N-1 的两条染色体与生物塑料生产菌 Ralstonia eutropha H16 的两个染色体复制子具有高度相似性。这两个菌株在质粒和氢化酶基因的存在上存在差异,N-1 菌株中不存在氢化酶基因。