Kozub P, Simaljakova M
Department of Dermatology, Faculty of Medicine, University Hospital, Bratislava, Slovakia.
Bratisl Lek Listy. 2011;112(7):390-4.
Methotrexate is the first line therapy for the treatment of moderate to severe psoriasis and psoriatic arthritis all over the world. It has immunosupressive and anti-inflammatory effects. If we want to use it, we have to know its mechanism of action and also its possible toxicity and how to cope with it (Tab. 3, Fig. 1, Ref. 14).
甲氨蝶呤是全球治疗中度至重度银屑病和银屑病关节炎的一线疗法。它具有免疫抑制和抗炎作用。如果我们想要使用它，就必须了解其作用机制、可能的毒性以及如何应对这些问题（表3、图1、参考文献14）。
