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Azithromycin treatment failure in Mycoplasma genitalium-positive patients with nongonococcal urethritis is associated with induced macrolide resistance.阿奇霉素治疗解脲脲原体阳性的非淋菌性尿道炎患者失败与诱导产生大环内酯类耐药有关。
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J Clin Microbiol. 2014 May;52(5):1549-55. doi: 10.1128/JCM.03318-13. Epub 2014 Feb 26.

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Mutations in ParC and GyrA of moxifloxacin-resistant and susceptible Mycoplasma genitalium strains.耐莫昔沙星和敏感的支原体生殖器菌株中 ParC 和 GyrA 的突变。
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infections: current treatment options and resistance issues.感染：当前的治疗选择与耐药问题
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Mycoplasma genitalium infection: current treatment options, therapeutic failure, and resistance-associated mutations.生殖支原体感染：当前的治疗选择、治疗失败及与耐药相关的突变
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本文引用的文献

1
Antimicrobial susceptibilities of Mycoplasma genitalium strains examined by broth dilution and quantitative PCR.解脲支原体株的药敏试验采用肉汤稀释法和定量 PCR 检测。
Antimicrob Agents Chemother. 2009 Nov;53(11):4938-9. doi: 10.1128/AAC.00724-09. Epub 2009 Sep 8.
2
A randomized comparison of azithromycin and doxycycline for the treatment of Mycoplasma genitalium-positive urethritis in men.阿奇霉素与强力霉素治疗男性生殖支原体阳性尿道炎的随机对照研究
Clin Infect Dis. 2009 Jun 15;48(12):1649-54. doi: 10.1086/599033.
3
Recombineering reveals a diverse collection of ribosomal proteins L4 and L22 that confer resistance to macrolide antibiotics.重组工程揭示了多种赋予对大环内酯类抗生素抗性的核糖体蛋白L4和L22。
J Mol Biol. 2009 Feb 20;386(2):300-15. doi: 10.1016/j.jmb.2008.12.064. Epub 2009 Jan 3.
4
Azithromycin treatment failure in Mycoplasma genitalium-positive patients with nongonococcal urethritis is associated with induced macrolide resistance.阿奇霉素治疗解脲脲原体阳性的非淋菌性尿道炎患者失败与诱导产生大环内酯类耐药有关。
Clin Infect Dis. 2008 Dec 15;47(12):1546-53. doi: 10.1086/593188.
5
Azithromycin failure in Mycoplasma genitalium urethritis.阿奇霉素治疗解脲脲原体尿道炎失败
Emerg Infect Dis. 2006 Jul;12(7):1149-52. doi: 10.3201/eid1207.051558.
6
Antibiotic susceptibility testing of Mycoplasma genitalium by TaqMan 5' nuclease real-time PCR.运用TaqMan 5'核酸酶实时PCR对生殖支原体进行抗生素敏感性测试。
Antimicrob Agents Chemother. 2005 Dec;49(12):4993-8. doi: 10.1128/AAC.49.12.4993-4998.2005.
7
Mycoplasma genitalium: the aetiological agent of urethritis and other sexually transmitted diseases.生殖支原体：尿道炎及其他性传播疾病的病原体。
J Eur Acad Dermatol Venereol. 2004 Jan;18(1):1-11. doi: 10.1111/j.1468-3083.2004.00923.x.
8
Mycoplasma genitalium: another important pathogen of nongonococcal urethritis.生殖支原体：非淋菌性尿道炎的另一种重要病原体。
J Urol. 2002 Mar;167(3):1210-7. doi: 10.1016/s0022-5347(05)65268-8.
9
Macrolide resistance conferred by base substitutions in 23S rRNA.23S核糖体RNA碱基置换导致的大环内酯类耐药性。
Antimicrob Agents Chemother. 2001 Jan;45(1):1-12. doi: 10.1128/AAC.45.1.1-12.2001.
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Isolation of Mycoplasma genitalium strains from the male urethra.从男性尿道中分离生殖支原体菌株。
J Clin Microbiol. 1996 Feb;34(2):286-91. doi: 10.1128/jcm.34.2.286-291.1996.

Macrolide resistance-associated 23S rRNA mutation in Mycoplasma genitalium, Japan.

作者信息

Shimada Yasushi, Deguchi Takashi, Nakane Keita, Yasuda Mitsuru, Yokoi Shigeaki, Ito Shin-Ichi, Nakano Masahiro, Ito Shin, Ishiko Hiroaki

出版信息

Emerg Infect Dis. 2011 Jun;17(6):1148-50. doi: 10.3201/eid/1706.101055.

DOI:10.3201/eid/1706.101055
PMID:21749801
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3358193/
Abstract
摘要