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A novel labda-7,13e-dien-15-ol-producing bifunctional diterpene synthase from Selaginella moellendorffii.

作者信息

Mafu Sibongile, Hillwig Matthew L, Peters Reuben J

机构信息

Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, 4216 Molecular Biology Building, Ames, IA 50011, USA.

出版信息

Chembiochem. 2011 Sep 5;12(13):1984-7. doi: 10.1002/cbic.201100336. Epub 2011 Jul 12.

DOI:10.1002/cbic.201100336
PMID:21751328
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3383829/
Abstract
摘要

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本文引用的文献

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The family of terpene synthases in plants: a mid-size family of genes for specialized metabolism that is highly diversified throughout the kingdom.植物萜类合酶家族:一个中等大小的基因家族,专门参与代谢,在整个生物界中高度多样化。
Plant J. 2011 Apr;66(1):212-29. doi: 10.1111/j.1365-313X.2011.04520.x.
2
Evident and latent plasticity across the rice diterpene synthase family with potential implications for the evolution of diterpenoid metabolism in the cereals.在水稻二萜合酶家族中存在明显和潜在的可塑性,这可能对谷物中二萜类代谢物的进化有影响。
Biochem J. 2011 May 1;435(3):589-95. doi: 10.1042/BJ20101429.
3
Characterization of the Rv3378c gene product, a new diterpene synthase for producing tuberculosinol and (13R, S)-isotuberculosinol (nosyberkol), from the Mycobacterium tuberculosis H37Rv genome.对来自结核分枝杆菌H37Rv基因组的Rv3378c基因产物的特性进行研究,该产物是一种用于产生结核菌素醇和(13R,S)-异结核菌素醇(诺西贝醇)的新型二萜合酶。
Biosci Biotechnol Biochem. 2011;75(1):75-81. doi: 10.1271/bbb.100570. Epub 2011 Jan 7.
4
CYP99A3: functional identification of a diterpene oxidase from the momilactone biosynthetic gene cluster in rice.CYP99A3:从水稻中的米那卡林生物合成基因簇中鉴定出一种二萜氧化酶。
Plant J. 2011 Jan;65(1):87-95. doi: 10.1111/j.1365-313X.2010.04408.x. Epub 2010 Nov 17.
5
Two rings in them all: the labdane-related diterpenoids.两者都有两个环:贝壳杉烷相关的二萜。
Nat Prod Rep. 2010 Nov;27(11):1521-30. doi: 10.1039/c0np00019a. Epub 2010 Oct 1.
6
A copal-8-ol diphosphate synthase from the angiosperm Cistus creticus subsp. creticus is a putative key enzyme for the formation of pharmacologically active, oxygen-containing labdane-type diterpenes.来自被子植物 Cretan 乳香黄连木亚种的 copal-8-ol 二磷酸合酶是形成具有药理活性的含氧 labdane 型二萜的假定关键酶。
Plant Physiol. 2010 Sep;154(1):301-10. doi: 10.1104/pp.110.159566. Epub 2010 Jul 1.
7
Synthesis of (+/-)-nosyberkol (isotuberculosinol, revised structure of edaxadiene) and (+/-)-tuberculosinol.(±)-nosyberkol(异土贝素醇,埃达甾二烯修订结构)和(±)-土贝素醇的合成。
Org Lett. 2010 Jun 4;12(11):2626-9. doi: 10.1021/ol100832h.
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Plant Cell. 2009 Oct;21(10):3315-25. doi: 10.1105/tpc.108.063677. Epub 2009 Oct 13.
10
Increasing diterpene yield with a modular metabolic engineering system in E. coli: comparison of MEV and MEP isoprenoid precursor pathway engineering.在大肠杆菌中用模块化代谢工程系统提高二萜产量:MEV 和 MEP 异戊二烯前体途径工程的比较。
Appl Microbiol Biotechnol. 2010 Feb;85(6):1893-906. doi: 10.1007/s00253-009-2219-x. Epub 2009 Sep 24.