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3-氯-4-二甲基氨基-5-[(1R,2S,5R)-2-异丙基-5-甲基环己氧基]呋喃-2(5H)-酮

3-Chloro-4-dimethyl-amino-5-[(1R,2S,5R)-2-isopropyl-5-methyl-cyclo-hex-yloxy]furan-2(5H)-one.

作者信息

Song Xiu-Mei, Wang Ning, Wang Zhao-Yang, Feng Zong-Cai

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2011 Jun 1;67(Pt 6):o1485-6. doi: 10.1107/S1600536811015583. Epub 2011 May 20.

DOI:10.1107/S1600536811015583
PMID:21754854
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3120571/
Abstract

The title compound, C(16)H(26)ClNO(3) contains one almost planar furan-one ring [maximum deviation of 0.021 (2) Å for the O atom] with a stereogenic center (S) and one cyclo-hexane ring which displays a chair conformation and has three stereogenic centers [S at the C atom bearing the isopropyl group, R at the C atom attached to the O atom and R at the C atom bearing the methyl group].

摘要

标题化合物C₁₆H₂₆ClNO₃含有一个几乎平面的呋喃-酮环[O原子的最大偏差为0.021(2) Å]，带有一个手性中心(S)和一个环己烷环，该环己烷环呈椅式构象且有三个手性中心[带有异丙基的C原子为S构型，与O原子相连的C原子为R构型，带有甲基的C原子为R构型]。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d80/3120571/34ba6809a66d/e-67-o1485-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d80/3120571/34ba6809a66d/e-67-o1485-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d80/3120571/34ba6809a66d/e-67-o1485-fig1.jpg

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A short history of SHELX.SHELX简史。
Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22. doi: 10.1107/S0108767307043930. Epub 2007 Dec 21.
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Synthesis and biological activities of a series of 4,5-diaryl-3-hydroxy-2(5H)-furanones.一系列4,5-二芳基-3-羟基-2(5H)-呋喃酮的合成及生物活性
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Bioactive constituents from Iryanthera megistophylla.大叶伊瑞樟的生物活性成分。
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The Cambridge Structural Database: a quarter of a million crystal structures and rising.剑桥结构数据库：拥有二十五万个晶体结构且数量不断增加。
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