（5S）-3-氯-4-二烯丙基氨基-5-[(1R,2S,5R)-2-异丙基-5-甲基环己氧基]呋喃-2(5H)-酮
(5S)-3-Chloro-4-diallyl-amino-5-[(1R,2S,5R)-2-isopropyl-5-methyl-cyclo-hex-yloxy]furan-2(5H)-one.
作者信息
Huang Dong-Na, Tan Yue-He, Fu Jian-Hua, Wang Zhao-Yang
机构信息
School of Chemistry and Environment, South China Normal University, Guangzhou 510006, People's Republic of China.
出版信息
Acta Crystallogr Sect E Struct Rep Online. 2011 Aug 1;67(Pt 8):o2050. doi: 10.1107/S1600536811027772. Epub 2011 Jul 16.
The title compound, C(20)H(30)ClNO(3), was obtained via a tandem asymmetric Michael addition-elimination reaction of (5S)-3,4-dichloro-5-(l-menth-yloxy)-2(5H)-furan-one and diallyl-amine in the presence of potassium fluoride. The mol-ecular structure contains an approximately planar five-membered furan-one ring [maximum atomic deviation = 0.0221 (3) Å] and a six-membered ring adopting a chair conformation.
标题化合物C(20)H(30)ClNO(3)是通过(5S)-3,4-二氯-5-(L-薄荷氧基)-2(5H)-呋喃酮与二烯丙基胺在氟化钾存在下进行串联不对称迈克尔加成-消除反应得到的。分子结构包含一个近似平面的五元呋喃酮环[最大原子偏差 = 0.0221 (3) Å]和一个采用椅式构象的六元环。
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