N-[(2S)-4-Chloro-2-(l-menthyloxy)-5-oxo-2,5-dihydro-3-furyl]-l-alanine.

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作者信息

Li Zhao-Yang, Song Xiu-Mei, Wang Zhao-Yang, Yang Kai

机构信息

School of Chemistry and Environment, South China Normal University, Guangzhou 510006, People's Republic of China.

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2009 Apr 10;65(Pt 5):o1030. doi: 10.1107/S1600536809012720.

DOI:10.1107/S1600536809012720

PMID:21583849

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2977713/

Abstract

The title compound, C(17)H(26)ClNO(5), was prepared via a tandem asymmetric Michael addition-elimination reaction of (5S)-3,4-dichloro-5-(l-menth-yloxy)furan-2(5H)--one and l-alanine in the presence of potassium hydroxide. The five-membered furan-one ring is approximately planar while the six-membered menth-yloxy ring adopts a chair conformation. The crystal packing is stabilized by inter-molecular O-H⋯O and N-H⋯O hydrogen bonds.

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e49f/2977713/a99a318cbacb/e-65-o1030-fig1.jpg

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