Structure elucidation of the new citharoxazole from the Mediterranean deep-sea sponge Latrunculia (Biannulata) citharistae.

作者信息

Genta-Jouve Grégory, Francezon Nellie, Puissant Alexandre, Auberger Patrick, Vacelet Jean, Pérez Thierry, Fontana Angelo, Mourabit Ali Al, Thomas Olivier P

机构信息

Laboratoire de Chimie des Molécules Bioactives et des Arômes UMR 6001 CNRS, Institut de Chimie de Nice, Faculté des Science, Université de Nice-Sophia Antipolis, Parc Valrose, 06108 Nice Cedex 02, France.

出版信息

Magn Reson Chem. 2011 Aug;49(8):533-6. doi: 10.1002/mrc.2772. Epub 2011 Jul 14.

DOI:10.1002/mrc.2772

PMID:21761452

Abstract

Citharoxazole (1), a new batzelline derivative featuring a benzoxazole moiety, was isolated from the Mediterranean deep-sea sponge Latrunculia (Biannulata) citharistae Vacelet, 1969, together with the known batzelline C (2). This is the first chemical study of a Mediterranean Latrunculia species and the benzoxazole moiety is unprecedented for this family of marine natural products. The structure was mainly elucidated by the interpretation of NMR spectra and especially HMBC correlations.

摘要