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手术在早期肾癌治疗中的作用。

The role of surgery in the management of early-stage renal cancer.

机构信息

Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, Weill Medical College, Cornell University, 1275 York Avenue, New York, NY 10021, USA.

出版信息

Hematol Oncol Clin North Am. 2011 Aug;25(4):737-52. doi: 10.1016/j.hoc.2011.04.009. Epub 2011 Jun 16.

DOI:10.1016/j.hoc.2011.04.009
PMID:21763965
Abstract

There were an estimated 58,240 new cases and 13,040 deaths from kidney cancer in the United States in 2010. The increased treatment and cure of small, incidentally discovered renal tumors, most of which are nonlethal in nature, has not offset the increased mortality caused by advanced and metastatic tumors. In this article, the optimum approach to the surgical management of localized renal tumors and its impact on renal function are discussed.

摘要

2010 年,美国估计有 58240 例新发病例和 13040 例肾癌死亡病例。虽然小的、偶然发现的肾肿瘤的治疗和治愈率有所提高,其中大多数肿瘤本质上并不致命,但这并没有抵消晚期和转移性肿瘤导致的死亡率增加。本文讨论了局部肾肿瘤的手术治疗的最佳方法及其对肾功能的影响。

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1
The role of surgery in the management of early-stage renal cancer.手术在早期肾癌治疗中的作用。
Hematol Oncol Clin North Am. 2011 Aug;25(4):737-52. doi: 10.1016/j.hoc.2011.04.009. Epub 2011 Jun 16.
2
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Laparoscopic nephrectomy for renal cell cancer: radical and total.腹腔镜肾切除术治疗肾细胞癌:根治性与全肾切除。
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The surgical approach to multifocal renal cancers: hereditary syndromes, ipsilateral multifocality, and bilateral tumors.多灶性肾癌的手术治疗:遗传性综合征、同侧多灶性和双侧肿瘤。
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Outcomes following partial nephrectomy by tumor size.根据肿瘤大小进行部分肾切除术后的结果。
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Laparoscopic radical versus partial nephrectomy for tumors >4 cm: intermediate-term oncologic and functional outcomes.腹腔镜根治性肾切除术与部分肾切除术治疗直径>4 cm肿瘤的中期肿瘤学及功能结局
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Open mini-flank partial nephrectomy: an essential contemporary operation.开放性微创侧腹部分肾切除术:一项重要的当代手术。
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The impact of genetic heterogeneity on biomarker development in kidney cancer assessed by multiregional sampling.通过多区域采样评估基因异质性对肾癌生物标志物开发的影响。
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PD-1 expression on peripheral blood cells increases with stage in renal cell carcinoma patients and is rapidly reduced after surgical tumor resection.PD-1 在肾细胞癌患者外周血细胞中的表达随疾病分期增加,在手术切除肿瘤后迅速降低。
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Role of metastasectomy for metastatic renal cell carcinoma in the era of targeted therapy.在靶向治疗时代,转移灶切除术对转移性肾细胞癌的作用。
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Oncological and renal medical importance of kidney-sparing surgery.保肾手术的肿瘤学和肾脏医学重要性。
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