先天性巨结肠病小肠结肠炎的微生物学研究
Microbiological studies of the enterocolitis of Hirschsprung's disease.
作者信息
Wilson-Storey D, Scobie W G, McGenity K G
机构信息
Subdepartment of Paediatric Surgery, Children's Hospital, Sheffield.
出版信息
Arch Dis Child. 1990 Dec;65(12):1338-9. doi: 10.1136/adc.65.12.1338.
Abstract
The results of a prospective study of 20 cases of newly diagnosed Hirschsprung's disease (nine of whom developed enterocolitis) and 10 normal controls showed no variations in the bacterial flora (including Clostridium difficile) in the stools of the groups studied. Viral studies showed that rotavirus was present in the stools of seven of the nine cases of enterocolitis during the episode. We suggest that Hirschsprung's enterocolitis may have a complex infective aetiology and that rotavirus plays a part.
摘要
一项针对20例新诊断的先天性巨结肠病患者（其中9例发生小肠结肠炎）和10名正常对照者的前瞻性研究结果显示，所研究组的粪便中细菌菌群（包括艰难梭菌）无差异。病毒学研究表明，在小肠结肠炎发作期间，9例中有7例的粪便中存在轮状病毒。我们认为，先天性巨结肠病小肠结肠炎可能有复杂的感染病因，轮状病毒在其中起一定作用。
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