Coners Kristin, Woods Scott E, Webb Michael
Bethesda Family Medicine Residency Program, 4411 Montgomery Road, Suite 200, Cincinnati, OH 45212, USA.
J Med Case Rep. 2011 Jul 19;5:318. doi: 10.1186/1752-1947-5-318.
We describe the case of a patient with small cell lung cancer and dual paraneoplastic syndromes involving adrenocorticotropic hormone and calcitonin. To the best of our knowledge, dual paraneoplastic syndromes involving these two hormones have not been previously reported in the literature.
A 74-year-old Caucasian woman presented with a left hilar mass and metastatic disease in the liver and right adrenal gland. The patient complained only of intermittent diarrhea. Her laboratory values exhibited metabolic alkalosis with hypokalemia, hypocalcemia, hypomagnesemia, hypophosphatemia, and hyperglycemia.
We discuss the work-up and treatment of the patient's unusual laboratory presentation with two concurrent paraneoplastic syndromes.
我们描述了一例患有小细胞肺癌并伴有涉及促肾上腺皮质激素和降钙素的双重副肿瘤综合征的患者。据我们所知,此前文献中尚未报道过涉及这两种激素的双重副肿瘤综合征。
一名74岁的白种女性患者,表现为左肺门肿块以及肝脏和右肾上腺转移瘤。患者仅主诉间歇性腹泻。其实验室检查结果显示为代谢性碱中毒伴低钾血症、低钙血症、低镁血症、低磷血症和高血糖。
我们讨论了该患者伴有两种并发副肿瘤综合征的异常实验室表现的检查及治疗情况。