Department of Experimental Oncology, European Institute of Oncology, Milan, Italy.
J Leukoc Biol. 2011 Oct;90(4):669-72. doi: 10.1189/jlb.0311141. Epub 2011 Jul 19.
DCs in the gut have specialized functions and are involved in maintaining intestinal homeostasis via tolerizing the microbiota and inducing immunity to pathogenic bacteria. Here, we summarize the characteristics of two major subtypes of phagocytes in the gut (CX3CR1(+) and CD103(+)) and pDCs and analyze their possible involvement in bacterial handling.
肠道中的树突状细胞（DCs）具有特定的功能，通过耐受微生物群和诱导对病原菌的免疫来维持肠道内稳态。在这里，我们总结了肠道中两种主要吞噬细胞亚型（CX3CR1(+)和 CD103(+))和浆细胞样树突状细胞（pDCs）的特征，并分析了它们在细菌处理中的可能作用。
