在阿谢曼综合征中生成容受性子宫内膜。
Generating receptive endometrium in Asherman's syndrome.
作者信息
Gargett Caroline E, Healy David L
机构信息
The Ritchie Centre, Monash Institute of Medical Research, Clayton Road, Victoria, Australia.
出版信息
J Hum Reprod Sci. 2011 Jan;4(1):49-52.
Abstract
Intrauterine administration of bone marrow stem/progenitor cells to a woman with thin endometrium refractory to estrogen stimulation regenerated her endometrium sufficiently to support a pregnancy. Or was it local endometrial damage induced by concurrent curettage that stimulated endogenous endometrial stem/progenitor cells into action? Or both?
摘要
对一名雌激素刺激无效的薄子宫内膜女性进行宫内注射骨髓干/祖细胞，使其子宫内膜充分再生以支持妊娠。或者是同时进行的刮宫术引起的局部子宫内膜损伤刺激了内源性子宫内膜干/祖细胞发挥作用？还是两者皆有？
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本文引用的文献
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Endometrial regeneration using autologous adult stem cells followed by conception by in vitro fertilization in a patient of severe Asherman's syndrome.在一名重度阿谢曼综合征患者中，使用自体成体干细胞进行子宫内膜再生，随后通过体外受精受孕。
J Hum Reprod Sci. 2011 Jan;4(1):43-8. doi: 10.4103/0974-1208.82360.
2
Bone marrow and circulating stem/progenitor cells for regenerative cardiovascular therapy.骨髓和循环中的干细胞/祖细胞用于心血管再生治疗。
Transl Res. 2010 Sep;156(3):112-29. doi: 10.1016/j.trsl.2010.06.008.
3
Adult stem cells in the endometrium.子宫内膜中的成人干细胞。
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