National Development and Research Institutes Inc, Public Health Solutions, New York, NY, USA.
J Urban Health. 2011 Dec;88(6):1020-30. doi: 10.1007/s11524-011-9600-7.
Prevention Point Pittsburgh (PPP) is a public health advocacy organization that operates Allegheny County's only needle exchange program. In 2002, PPP implemented an Overdose Prevention Program (OPP) in response to an increase in heroin-related and opioid-related overdose fatalities in the region. In 2005, the OPP augmented overdose prevention and response trainings to include naloxone training and prescription. The objective of our study is to describe the experiences of 426 individuals who participated in the OPP between July 1, 2005, and December 31, 2008. Of these, 89 individuals reported administering naloxone in response to an overdose in a total of 249 separate overdose episodes. Of these 249 overdose episodes in which naloxone was administered, participants reported 96% were reversed. The data support findings from a growing body of research on similar programs in other cities. Community-based OPPs that equip drug users with skills to identify and respond to an overdose and prescribe naloxone can help users and their peers prevent and reverse potentially fatal overdoses without significant adverse consequences.
预防点匹兹堡（PPP）是一个公共卫生倡导组织，负责运营阿勒格尼县唯一的针具交换计划。2002 年，PPP 实施了一项过量预防计划（OPP），以应对该地区与海洛因和类阿片相关的过量死亡人数增加。2005 年，OPP 扩大了过量预防和应对培训，包括纳洛酮培训和处方。我们的研究目的是描述 2005 年 7 月 1 日至 2008 年 12 月 31 日期间参与 OPP 的 426 人的经验。其中，89 人报告在 249 次单独的过量用药事件中使用了纳洛酮进行抢救。在这些接受纳洛酮抢救的 249 次过量用药事件中，报告称 96%的情况得到逆转。这些数据支持了来自其他城市类似项目的越来越多研究结果。为吸毒者提供识别和应对过量用药并开具纳洛酮技能的基于社区的 OPP，可以帮助吸毒者及其同伴预防和逆转潜在致命的过量用药，而不会产生重大不良后果。
