Murthy Vinaya S, Garza Mary A, Almario Donna A, Vogel Kristen J, Grubs Robin E, Gettig Elizabeth A, Wilson John W, Thomas Stephen B
Department of Clinical Genetics, The Permanente Medical Group, San Jose, CA 95123, USA.
J Genet Couns. 2011 Dec;20(6):639-49. doi: 10.1007/s10897-011-9389-2. Epub 2011 Jul 20.
Few studies examine the use of family history to influence risk perceptions in the African American population. This study examined the influence of a family health history (FHH) intervention on risk perceptions for breast (BRCA), colon (CRC), and prostate cancers (PRCA) among African Americans in Pittsburgh, PA. Participants (n = 665) completed pre- and post-surveys and FHHs. We compared their objective and perceived risks, classified as average, moderate, or high, and examined the accuracy of risk perceptions before and after the FHH intervention. The majority of participants had accurate risk perceptions post-FHH. Of those participants who were inaccurate pre-FHH, 43.3%, 43.8%, and 34.5% for BRCA, CRC, and PRCA, respectively, adopted accurate risk perceptions post-FHH intervention. The intervention was successful in a community setting. It has the potential to lead to healthy behavior modifications because participants adopted accurate risk perceptions. We identified a substantial number of at-risk individuals who could benefit from targeted prevention strategies, thus decreasing racial/ethnic cancer disparities.
很少有研究探讨利用家族病史来影响非裔美国人的风险认知。本研究考察了家族健康史（FHH）干预对宾夕法尼亚州匹兹堡市非裔美国人乳腺癌（BRCA）、结肠癌（CRC）和前列腺癌（PRCA）风险认知的影响。参与者（n = 665）完成了干预前后的调查及家族健康史调查。我们比较了他们客观和感知到的风险，分为低、中、高三个等级，并考察了FHH干预前后风险认知的准确性。大多数参与者在FHH干预后有准确的风险认知。在FHH干预前认知不准确的参与者中，BRCA、CRC和PRCA分别有43.3%、43.8%和34.5%在FHH干预后采用了准确的风险认知。该干预在社区环境中是成功的。由于参与者采用了准确的风险认知，它有可能导致健康行为的改变。我们识别出大量有风险的个体，他们可以从有针对性的预防策略中受益，从而减少种族/族裔间的癌症差异。
