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丹麦双胞胎登记处。

The Danish Twin Registry.

机构信息

The Danish Twin Registry, Epidemiology, Institute of Public Health, University of Southern Denmark, Odense, Denmark.

出版信息

Scand J Public Health. 2011 Jul;39(7 Suppl):75-8. doi: 10.1177/1403494810387966.

DOI:10.1177/1403494810387966
PMID:21775358
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3350839/
Abstract

INTRODUCTION

The Danish Twin Registry is a unique source for studies of genetic, familial and environmental factors on life events, health conditions and diseases.

CONTENT

More than 85,000 twin pairs born 1870-2008 in Denmark.

VALIDITY AND COVERAGE

Four main ascertainment methods have been employed. Completeness of ascertainment varies according to birth cohorts. For birth cohorts 1870-1930 both twins should survive to age 6 years. From 1931-1968 72% of all twin pairs has been ascertained, with complete ascertainment of all live born twins since 1968.

CONCLUSION

Because twins have been identified independent of traits and on a population basis, the Danish Twin Registry is well suited for studies to understand the influence of genetic and environmental factors for a wide variety of diseases and traits.

摘要

简介

丹麦双胞胎登记处是一个独特的资源,可用于研究遗传、家庭和环境因素对生活事件、健康状况和疾病的影响。

内容

登记处包含了超过 85000 对出生于 1870 年至 2008 年的丹麦双胞胎。

有效性和覆盖范围

采用了四种主要的确定方法。根据出生队列,确定的完整性有所不同。对于 1870 年至 1930 年的出生队列,双胞胎都应活到 6 岁。从 1931 年至 1968 年,已经确定了 72%的双胞胎,自 1968 年以来已经完全确定了所有活产双胞胎。

结论

由于双胞胎是在不考虑特征的情况下,基于人群被识别出来的,因此丹麦双胞胎登记处非常适合研究各种疾病和特征的遗传和环境因素的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71f8/3350839/cf67e9738c48/nihms372833f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71f8/3350839/cf67e9738c48/nihms372833f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71f8/3350839/cf67e9738c48/nihms372833f1.jpg

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Age- and sex-differences in the validity of questionnaire-based zygosity in twins.双胞胎中基于问卷的合子性判定有效性的年龄和性别差异。
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Cognition is selectively impaired in males with spinal pain: A retrospective analysis of data from the Longitudinal Study of Ageing Danish Twins.
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