丹麦双胞胎登记处。

The Danish Twin Register.

作者信息

Kyvik K O, Christensen K, Skytthe A, Harvald B, Holm N V

机构信息

Odense University, Genetic Epidemiological Research Group.

出版信息

Dan Med Bull. 1996 Dec;43(5):467-70.

PMID:8960820

Abstract

BACKGROUND

Population based twin registers represent a valuable tool for genetic epidemiological research, since twin studies aim at separating the effect of genes and environment for complex traits. The Danish Twin Register's history, size, ascertainment and completeness of data, as well as data accessibility and availability are described.

RESULTS

The Danish Twin Register comprises 14,051 twin pairs born 1870-1930, representing all twins surviving to age six years, and 20,888 twin pairs born 1953-1982, representing 75% of those born 1953-1967 and 95% of those born 1968-1982. The birth cohorts 1931-1952 og 1983-1993 are being ascertained at the moment. The register is available for research given certain conditions are fulfilled.

CONCLUSION

This register will in a few years be the most comprehensive twin register in the world. It is a very valuable Danish research resource.

摘要

背景

基于人群的双胞胎登记册是遗传流行病学研究的宝贵工具，因为双胞胎研究旨在区分基因和环境对复杂性状的影响。本文描述了丹麦双胞胎登记册的历史、规模、数据的确定与完整性，以及数据的可获取性和可用性。

结果

丹麦双胞胎登记册包含1870年至1930年出生的14,051对双胞胎，代表了所有存活至6岁的双胞胎；以及1953年至1982年出生的20,888对双胞胎，分别占1953年至1967年出生人数的75%和1968年至1982年出生人数的95%。目前正在确定1931年至1952年和1983年至1993年的出生队列。在满足一定条件的情况下，该登记册可供研究使用。