Center for Motility and Functional Gastrointestinal Disorders, Children's Hospital Boston, Boston, MA 02115, USA.
J Pediatr. 2011 Sep;159(3):504-6. doi: 10.1016/j.jpeds.2011.05.021. Epub 2011 Jul 21.
The aim of the study was to determine if children with chronic cough or wheezing and with more full-column, nonacid reflux have a higher likelihood of a positive bronchoalveolar lavage fluid culture. In a prospective study of 46 children with cough who were undergoing endoscopy, multichannel intraluminal impedance testing, and bronchoscopy, we found that patients who had a positive culture had significantly more full-column, nonacid gastroesophageal reflux than those who had a negative culture.
本研究旨在确定是否患有慢性咳嗽或喘息且存在更多全柱、非酸性反流的儿童,其支气管肺泡灌洗液培养阳性的可能性更高。在一项对 46 名接受内镜检查、多通道腔内阻抗测试和支气管镜检查的咳嗽患儿进行的前瞻性研究中,我们发现,培养阳性的患者全柱、非酸性胃食管反流明显多于培养阴性的患者。