Gaertner Jan, Wuerstlein Rachel, Ostgathe Christoph, Mallmann Peter, Harbeck Nadia, Voltz Raymond
Department of Palliative Medicine, University Hospital Cologne, Germany.
Breast Care (Basel). 2011;6(3):240-244. doi: 10.1159/000329007. Epub 2011 Jun 3.
To comply with patients' needs as well as ASCO and WHO recommendations, our institution aims to integrate palliative care (PC) early in the course of breast cancer (BC) therapy. The evaluation of relevant pilot project data revealed that these recommendations were too vague to trigger PC integration. Therefore, a standard operating procedure (SOP) was developed by our interdisciplinary working group to provide disease-specific information to overcome the ambiguity of the WHO recommendations and guide PC integration. Literally, the SOP states that 'Specialized PC is recommended regularly for all BC patients without curative treatment options, specifically for patients with i) metastasized and inoperable, or ii) locally advanced and inoperable, or iii) relapsing BC, who are receiving intravenous chemotherapy'. This SOP for the first time presents disease-specific guidelines for PC integration into comprehensive BC therapy by defining 'green flags' for early integration of PC and delineating PC from senology assignments. Although disease-specific SOPs have also been developed by this working group for other malignancies, the decision when to first integrate PC into BC therapy differs substantially because of the different clinical characteristics of the disease.
为了满足患者需求以及美国临床肿瘤学会(ASCO)和世界卫生组织(WHO)的建议,我们机构旨在在乳腺癌(BC)治疗过程中尽早纳入姑息治疗(PC)。对相关试点项目数据的评估显示,这些建议过于模糊,无法推动PC的纳入。因此,我们的跨学科工作组制定了一份标准操作程序(SOP),以提供针对特定疾病的信息,克服WHO建议的模糊性,并指导PC的纳入。确切地说,SOP规定“对于所有没有治愈性治疗选择的BC患者,特别是对于以下患者,建议定期进行专业PC:i)转移性且无法手术的患者,或ii)局部晚期且无法手术的患者,或iii)正在接受静脉化疗的复发性BC患者”。该SOP首次通过定义PC早期纳入的“警示信号”并将PC与乳腺病任务区分开来,提出了将PC纳入综合BC治疗的针对特定疾病的指南。尽管该工作组也为其他恶性肿瘤制定了针对特定疾病的SOP,但由于该疾病的临床特征不同,首次将PC纳入BC治疗的时机差异很大。