Department of Nutrition and Dietetics, Faculty of Allied Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
Physiol Behav. 2011 Oct 24;104(5):1059-64. doi: 10.1016/j.physbeh.2011.07.007. Epub 2011 Jul 18.
Calorie restriction (CR) has been promoted to increase longevity. Previous studies have indicated that CR can negatively affect mood and therefore the effect of CR on mood and quality of life (QOL) becomes crucial when considering the feasibility of CR in humans. We conducted a three month clinical trial on CR (reduction of 300 to 500 kcal/day) combined with two days/week of Muslim sunnah fasting (FCR) to determine the effectiveness of FCR on QOL among aging men in Klang Valley, Malaysia. A total of 25 healthy Malay men (age 58.8±5.1 years), with no chronic diseases and a BMI of 23.0 to 29.9 kg/m2 were randomized to FCR (n=12) and control (n=13) groups. Body composition measurements and QOL questionnaires were ascertained at baseline, week 6 and week 12. QOL was measured using the Short-Form 36, sleep quality was determined using the Pittsburgh Sleep Quality Index, the Beck Depression Inventory II was used to measure mood and the Perceived Stress Scale was used to measure depression. The FCR group had a significant reduction in body weight, BMI, body fat percentage and depression (P<0.05). The energy component of QOL was significantly increased in FCR group (p<0.05). There were no significant changes in sleep quality and stress level between the groups as a result of the intervention. In conclusion, FCR resulted in body weight and fat loss and alleviated depression with some improvement in the QOL in our study and has the potential to be implemented on a wider scale.
热量限制（CR）已被推广用于延长寿命。先前的研究表明，CR 可能会对情绪产生负面影响，因此在考虑 CR 对人类可行性时，CR 对情绪和生活质量（QOL）的影响至关重要。我们进行了一项为期三个月的临床研究，研究了热量限制（每天减少 300 至 500 卡路里）与穆斯林苏纳法禁食（FCR）相结合对马来西亚 Klang Valley 老年男性 QOL 的影响。共有 25 名健康的马来男性（年龄 58.8±5.1 岁），无慢性疾病，BMI 为 23.0 至 29.9 kg/m2，随机分为 FCR（n=12）和对照组（n=13）。在基线、第 6 周和第 12 周测量身体成分和 QOL 问卷。使用 36 项简短健康调查问卷（SF-36）测量 QOL，使用匹兹堡睡眠质量指数（PSQI）确定睡眠质量，使用贝克抑郁量表 II（BDI-II）测量情绪，使用感知压力量表（PSS）测量抑郁。FCR 组体重、BMI、体脂百分比和抑郁显著降低（P<0.05）。FCR 组的生活质量的能量成分显著增加（p<0.05）。干预后，两组的睡眠质量和压力水平均无显著变化。总之，FCR 导致体重和脂肪减少，缓解抑郁，在我们的研究中，生活质量有一定程度的改善，并且有可能在更广泛的范围内实施。
