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结直肠癌患者的生活质量与症状管理障碍

Quality of life and barriers to symptom management in colon cancer.

机构信息

City of Hope - Nursing Research and Education, 1500 East Duarte Road, Duarte, CA 91010, USA.

出版信息

Eur J Oncol Nurs. 2012 Jul;16(3):276-80. doi: 10.1016/j.ejon.2011.06.011. Epub 2011 Jul 23.

Abstract

PURPOSE OF THE RESEARCH

Pain and fatigue are recognized as critical symptoms that impact QOL for patients with colon cancer. Barriers to optimum pain and fatigue relief include patient-related beliefs and attitudes about the treatment of cancer-related symptoms. The overall objective of this paper was to describe quality of life (QOL) and barriers to pain and fatigue management in patients with colon cancer.

METHODS AND SAMPLE

This longitudinal, descriptive study included was conducted in the ambulatory clinic of one NCI-designated comprehensive cancer center. A cohort of 56 patients with colon cancer and a pain and/or fatigue of ≥4 (moderate to severe) was recruited. Subjects completed questionnaires to assess subjective ratings of overall QOL, fatigue, barriers to pain and fatigue, and pain and fatigue knowledge.

KEY RESULTS

The majority of subjects (58%) reported having moderate to severe (4-6) fatigue at the time of accrual. Overall QOL score was moderate (M = 5.20, SD = 1.43), and the social well-being subscale had the lowest score (M = 4.57, SD = 1.82). Patient barriers to pain and fatigue existed in attitudes and beliefs regarding addiction, tolerance, and that fatigue is an inevitable part of cancer and its treatments. Patient knowledge of pain and fatigue was high (77%-88% correct), but lack of knowledge persisted in areas such as addiction to pain medications and utilizing physical activity to manage fatigue.

CONCLUSIONS

Several patient-related attitudes and beliefs may hinder optimum relief of symptoms such as pain and fatigue. Social well-being may be a major determinant of overall QOL for patients with colon cancer.

摘要

研究目的

疼痛和疲劳被认为是影响结肠癌患者生活质量的关键症状。影响疼痛和疲劳缓解的最佳效果的障碍包括患者对癌症相关症状治疗的相关信念和态度。本文的总体目标是描述结肠癌患者的生活质量(QOL)和疼痛及疲劳管理障碍。

方法和样本

这是一项在一家 NCI 指定的综合癌症中心的门诊诊所进行的纵向描述性研究。招募了 56 名患有结肠癌且疼痛和/或疲劳≥4 分(中重度)的患者。受试者完成了问卷,以评估总体 QOL、疲劳、疼痛和疲劳管理障碍以及疼痛和疲劳知识的主观评分。

主要结果

大多数受试者(58%)在入组时报告有中重度(4-6 分)疲劳。总体 QOL 评分为中等(M=5.20,SD=1.43),社会福祉子量表得分最低(M=4.57,SD=1.82)。患者在成瘾、耐受性以及疲劳是癌症及其治疗不可避免的一部分的观念和信念方面存在疼痛和疲劳的障碍。患者对疼痛和疲劳的知识水平较高(77%-88%正确),但在成瘾性止痛药和利用体育活动来管理疲劳等方面的知识仍然存在不足。

结论

一些与患者相关的态度和信念可能会阻碍疼痛和疲劳等症状的最佳缓解。社会福祉可能是结肠癌患者总体 QOL 的主要决定因素。

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