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腰椎骨质疏松性椎体骨折所致神经根病

Radiculopathy caused by osteoporotic vertebral fractures in the lumbar spine.

作者信息

Sasaki Manabu, Aoki Masanori, Nishioka Kazuya, Yoshimine Toshiki

机构信息

Department of Neurosurgery, Iseikai Hospital, Osaka, Japan.

出版信息

Neurol Med Chir (Tokyo). 2011;51(7):484-9. doi: 10.2176/nmc.51.484.

DOI:10.2176/nmc.51.484
PMID:21785241
Abstract

The clinical features of radiculopathy caused by osteoporotic vertebral fractures (OVFs) in the lumbar spine were investigated in 66 patients treated for pain caused by OVFs from January 2006 to December 2009. Ten of the patients complained of persistent radiculopathy. The cause of radiculopathy was initially diagnosed as lumbar canal stenosis (LCS) in seven patients, lumbar foraminal stenosis (LFS) in two, and both in one. One patient with LFS had reduced pain with conservative treatment, and the other nine needed surgical treatments. LCS was treated with posterior decompression, and LFS complicated with LCS at the same spinal level was treated with posterior lumbar interbody fusion (PLIF). Vertebroplasty was performed for one patient with LFS to attain indirect nerve root decompression achieved as a result of vertebral reconstruction and stabilization. Four of the patients treated with posterior decompression for LCS suffered from residual radiculopathy postoperatively, which was caused by LFS at the same level or the level below the treated level. Two patients underwent second operative procedure (PLIF) for recurrent radiculopathy. The Japanese Orthopedic Association and Visual Analogue Scale scores of the pain improved after operations, but the scores of the patients treated without spinal fusion gradually worsened during the follow-up period, whereas the scores of the patients treated with PLIF remained stable at various levels. Seven of the ten patients developed LFS following OVF, suggesting that radiculopathy following OVF involves LFS with high frequency.

摘要

对2006年1月至2009年12月间因骨质疏松性椎体骨折(OVF)所致疼痛而接受治疗的66例患者,研究了腰椎OVF引起的神经根病的临床特征。其中10例患者主诉持续性神经根病。神经根病的病因最初诊断为7例腰椎管狭窄(LCS)、2例腰椎椎间孔狭窄(LFS)、1例两者并存。1例LFS患者经保守治疗疼痛减轻,其他9例需要手术治疗。LCS采用后路减压治疗,同一脊柱节段LFS合并LCS者采用后路腰椎椎间融合术(PLIF)治疗。对1例LFS患者行椎体成形术,以通过椎体重建和稳定实现间接神经根减压。4例因LCS接受后路减压治疗的患者术后出现残余神经根病,原因是同一节段或治疗节段以下的LFS。2例患者因复发性神经根病接受了二次手术(PLIF)。术后日本骨科协会评分和视觉模拟量表疼痛评分均有改善,但未行脊柱融合术治疗的患者评分在随访期间逐渐恶化,而行PLIF治疗的患者评分在各水平均保持稳定。10例患者中有7例在OVF后发生LFS,提示OVF后的神经根病高频累及LFS。

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