Hospital General Dr. Manuel Gea Gonzalez, SSA, Calzada de Tlalpan 4800, Col Seccion XVI, Tlalpan, Mexico 14080 DF.
Parasit Vectors. 2011 Jul 25;4:147. doi: 10.1186/1756-3305-4-147.
The life cycle of Taenia pisiformis includes canines as definitive hosts and rabbits as intermediate hosts. Golden hamster (Mesocricetus auratus) is a rodent that has been successfully used as experimental model of Taenia solium taeniosis. In the present study we describe the course of T. pisiformis infection in experimentally infected golden hamsters. Ten females, treated with methyl-prednisolone acetate were infected with three T. pisiformis cysticerci each one excised from one rabbit. Proglottids released in faeces and adults recovered during necropsy showed that all animals were infected. Eggs obtained from the hamsters' tapeworms, were assessed for viability using trypan blue or propidium iodide stains. Afterwards, some rabbits were inoculated with eggs, necropsy was performed after seven weeks and viable cysticerci were obtained. Our results demonstrate that the experimental model of adult Taenia pisiformis in golden hamster can replace the use of canines in order to study this parasite and to provide eggs and adult tapeworms to be used in different types of experiments.
豆状带绦虫的生命周期包括犬类作为终宿主和兔类作为中间宿主。金黄仓鼠(Mesocricetus auratus)是一种啮齿动物,已成功用作猪带绦虫囊尾蚴病的实验模型。在本研究中,我们描述了实验感染金黄仓鼠感染豆状带绦虫的过程。用醋酸甲泼尼龙龙处理的 10 只雌性仓鼠,每只仓鼠感染了从一只兔子身上切除的三个豆状带绦虫囊尾蚴。从粪便中释放的节片和尸检中回收的成虫表明,所有动物都受到了感染。用台盼蓝或碘化丙啶染色评估从仓鼠绦虫中获得的卵的活力。之后,一些兔子接种了卵,七周后进行尸检,获得了存活的囊尾蚴。我们的结果表明,金黄仓鼠成年豆状带绦虫的实验模型可以替代犬类用于研究这种寄生虫,并提供卵和成虫绦虫,用于不同类型的实验。